PPP1R8 and WDR77

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid)

		PPP1R8	WDR77
Description		protein phosphatase 1 regulatory subunit 8	WD repeat domain 77
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Nuclear Speck	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Methylosome
	Molecular Function	DNA Binding RNA Binding MRNA Binding Endonuclease Activity Protein Serine/threonine Phosphatase Inhibitor Activity Protein Binding Ribonuclease E Activity	Protein Binding Methyl-CpG Binding Nuclear Receptor Transcription Coactivator Activity
	Biological Process	MRNA Processing RNA Catabolic Process Cell Proliferation RNA Splicing Negative Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Protein Dephosphorylation RNA Phosphodiester Bond Hydrolysis	Spliceosomal SnRNP Assembly Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Proliferation Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Nucleic Acid-templated Transcription
Pathways			snRNP Assembly RMTs methylate histone arginines
Drugs
Diseases
GWAS
Interacting Genes		26 interacting genes: APP APPBP2 CDC5L CREBBP CRMP1 CSNK2A1 CSNK2A2 CTNNBL1 EED ERG28 FBXO25 GBP2 HDAC2 HMGA1 LRRK2 LYN MELK PPIL1 PPP1CA PPP1CC PRKACA RBM48 SETDB1 SF3B1 STC2 WDR77	44 interacting genes: AQR BAG2 CDK19 CDK8 CLNS1A CREBBP CTDP1 GLI1 GPKOW H2AC21 HNRNPM LSM3 NKX3-1 PCBP2 PITRM1 PPIL1 PPP1R8 PQBP1 PRKG1 PRKG2 PRMT5 QKI RBM5 RIOK1 SAP30BP SF1 SF3A1 SF3B4 SIRT7 SMAD1 SMYD1 SNRPB SNRPC SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SUZ12 THOC1 TOE1 YWHAB YWHAQ ZNF207
Entrez ID		5511	79084
HPRD ID		04028	14387
Ensembl ID		ENSG00000117751	ENSG00000116455
Uniprot IDs		Q12972 Q6ICT4	A0A024R0H7 Q9BQA1
PDB IDs		3V4Y	4GQB 4X60 4X61 4X63 5C9Z 5EMJ 5EMK 5EML 5EMM 5FA5 6CKC 6K1S
Enriched GO Terms of Interacting Partners?
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