MRPL20 and USP13

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MRPL20	USP13
Description		mitochondrial ribosomal protein L20	ubiquitin specific peptidase 13
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Ribosome Mitochondrial Large Ribosomal Subunit	Nucleoplasm Cytosol
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding RRNA Binding	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Thiol-dependent Ubiquitinyl Hydrolase Activity Ubiquitin Binding Ubiquitin-like Protein Ligase Binding Chaperone Binding Proteasome Binding BAT3 Complex Binding Lys48-specific Deubiquitinase Activity
	Biological Process	Ribosomal Large Subunit Assembly Mitochondrial Translational Elongation Mitochondrial Translational Termination	Regulation Of Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Autophagy Cell Proliferation Regulation Of Autophagy Protein Deubiquitination Melanocyte Differentiation Protein K29-linked Deubiquitination Protein K6-linked Deubiquitination Protein Stabilization Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Positive Regulation Of ERAD Pathway Maintenance Of Unfolded Protein Involved In ERAD Pathway
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination	Ub-specific processing proteases Regulation of PTEN stability and activity
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30578418) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)
Interacting Genes		10 interacting genes: ACP1 APP CALM2 CAPZB DUSP23 EPS8 ITSN1 OXA1L TP53BP2 USP13	23 interacting genes: AMFR BAG6 DVL1 FNBP1L FUNDC2 GPR160 HSP90AA1 LAPTM5 MCL1 MDC1 MRPL20 MYO15A PTEN S100A9 SIAH2 SPRR2C SYCP2 TRA2B TRIM55 TRIM63 UBC UBL4A UIMC1
Entrez ID		55052	8975
HPRD ID		14746	04666
Ensembl ID		ENSG00000242485	ENSG00000058056
Uniprot IDs		Q9BYC9	A0A0A6YZ17 Q92995
PDB IDs		3J7Y 3J9M 5OOL 5OOM 6NU2 6NU3	2L80 2LBC
Enriched GO Terms of Interacting Partners?
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