VPS37C and VPS28

Number of citations of the paper that reports this interaction (PubMedID 21757351)
41

Data Source:
BioGRID (pull down, affinity chromatography technology)

		VPS37C	VPS28
Description		VPS37C subunit of ESCRT-I	VPS28 subunit of ESCRT-I
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	ESCRT I Complex Endosome Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle Host Cell Extracellular Exosome	ESCRT I Complex Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Endosome Membrane Late Endosome Membrane Host Cell Extracellular Exosome
	Molecular Function	Protein Binding Calcium-dependent Protein Binding	Protein Binding Ubiquitin Binding Protein-containing Complex Binding
	Biological Process	Protein Targeting To Membrane Protein Targeting To Vacuole Endosomal Transport Macroautophagy Viral Life Cycle Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Intracellular Transport Of Virus	Endosomal Transport Macroautophagy Viral Life Cycle Negative Regulation Of Protein Ubiquitination Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Protein Catabolic Process Intracellular Transport Of Virus Positive Regulation Of Ubiquitin-dependent Endocytosis
Pathways		Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy	Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
Drugs
Diseases
GWAS		Rheumatoid arthritis ( 23143596)	Blood metabolite levels ( 26401656) Educational attainment ( 25201988)
Interacting Genes		32 interacting genes: ABI2 APP C1orf94 CEP55 DAZAP2 DDIT3 FAM168A GOLGA2 HGS HNRNPUL1 MAPK1IP1L PDCD6 PDCD6IP PKNOX1 PLSCR1 PSMA3 RBPMS RFX6 RINT1 SH3GL1 SORBS2 SORBS3 STAM2 TACC3 TFG TFIP11 TLE5 TSG101 UBC VPS28 WWP2 XIAP	30 interacting genes: ASF1A BLZF1 CARD9 CBX5 CEP57L1 FABP3 GABARAP GLCCI1 GOLGA2 INCA1 MBIP PDCD6IP PNMA5 RASSF5 SAXO1 SKIL SMN1 SMN2 TCF12 TCF4 TRIM27 TRIM54 TSG101 UBA52 UBC USHBP1 VPS37A VPS37B VPS37C VPS52
Entrez ID		55048	51160
HPRD ID		15652	11675
Ensembl ID		ENSG00000167987	ENSG00000160948
Uniprot IDs		A5D8V6	A0A0S2Z5H5 Q548N1 Q9UK41
PDB IDs
Enriched GO Terms of Interacting Partners?
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