VPS28 and ASF1A

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		VPS28	ASF1A
Description		VPS28 subunit of ESCRT-I	anti-silencing function 1A histone chaperone
Image		No pdb structure
GO Annotations	Cellular Component	ESCRT I Complex Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Endosome Membrane Late Endosome Membrane Host Cell Extracellular Exosome	Nuclear Chromatin Nucleus Nucleoplasm Protein-containing Complex
	Molecular Function	Protein Binding Ubiquitin Binding Protein-containing Complex Binding	Chromatin Binding Protein Binding Histone Binding
	Biological Process	Endosomal Transport Macroautophagy Viral Life Cycle Negative Regulation Of Protein Ubiquitination Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Protein Catabolic Process Intracellular Transport Of Virus Positive Regulation Of Ubiquitin-dependent Endocytosis	Osteoblast Differentiation DNA Repair Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Negative Regulation Of Chromatin Silencing Muscle Cell Differentiation
Pathways		Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy	Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS		Blood metabolite levels ( 26401656) Educational attainment ( 25201988)	Multiple sclerosis ( 31604244) QT interval ( 19305408)
Interacting Genes		30 interacting genes: ASF1A BLZF1 CARD9 CBX5 CEP57L1 FABP3 GABARAP GLCCI1 GOLGA2 INCA1 MBIP PDCD6IP PNMA5 RASSF5 SAXO1 SKIL SMN1 SMN2 TCF12 TCF4 TRIM27 TRIM54 TSG101 UBA52 UBC USHBP1 VPS37A VPS37B VPS37C VPS52	22 interacting genes: ASF1B CDAN1 CHAF1A CHAF1B CHEK2 H3-3A H3-4 H3C3 H3C6 H4-16 H4C13 H4C6 HIRA HTATIP2 PAFAH1B2 PRR3 ST13 TAF1 TLK1 TLK2 VPS28 ZDHHC17
Entrez ID		51160	25842
HPRD ID		11675	16459
Ensembl ID		ENSG00000160948	ENSG00000111875
Uniprot IDs		A0A0S2Z5H5 Q548N1 Q9UK41	Q9Y294
PDB IDs			1TEY 2I32 2IIJ 2IO5 3AAD 5C3I 6F0F 6F0G 6F0H
Enriched GO Terms of Interacting Partners?
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