PHIP and CUL4A

Number of citations of the paper that reports this interaction (PubMedID 30018425)
3

Data Source:
BioGRID (pull down)

		PHIP	CUL4A
Description		pleckstrin homology domain interacting protein	cullin 4A
Image
GO Annotations	Cellular Component	Nucleus	Nucleoplasm SCF Ubiquitin Ligase Complex Cullin-RING Ubiquitin Ligase Complex Cul4A-RING E3 Ubiquitin Ligase Complex Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Insulin Receptor Binding Protein Binding Lysine-acetylated Histone Binding	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Regulation Of Protein Phosphorylation Regulation Of Transcription By RNA Polymerase II Cytoskeleton Organization Positive Regulation Of Cell Proliferation Insulin Receptor Signaling Pathway Regulation Of Cell Shape Regulation Of Cell Morphogenesis Negative Regulation Of Apoptotic Process Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Mitotic Nuclear Division Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	G1/S Transition Of Mitotic Cell Cycle Nucleotide-excision Repair, DNA Damage Recognition Nucleotide-excision Repair, DNA Duplex Unwinding In Utero Embryonic Development Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair, Preincision Complex Stabilization Nucleotide-excision Repair, Preincision Complex Assembly Nucleotide-excision Repair, DNA Incision, 3'-to Lesion Nucleotide-excision Repair, DNA Incision, 5'-to Lesion Ubiquitin-dependent Protein Catabolic Process Cellular Response To DNA Damage Stimulus Positive Regulation Of Cell Proliferation Viral Process Protein Ubiquitination Hemopoiesis Negative Regulation Of Granulocyte Differentiation SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Nucleotide-excision Repair, DNA Incision Somatic Stem Cell Population Maintenance Ribosome Biogenesis DNA Damage Response, Detection Of DNA Damage Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Rhythmic Process Regulation Of Protein Metabolic Process Global Genome Nucleotide-excision Repair Intrinsic Apoptotic Signaling Pathway Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of DNA Damage Checkpoint Regulation Of Nucleotide-excision Repair
Pathways			Recognition of DNA damage by PCNA-containing replication complex DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER Dual Incision in GG-NER Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Neddylation
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878 27618448) Intelligence (MTAG) ( 29326435) LDL cholesterol levels x loop diuretics use interaction ( 31806883) Mean arterial pressure ( 27618448) SjÃ¶gren's syndrome ( 24097067) Systolic blood pressure ( 27841878 30578418)	Atrial fibrillation ( 30061737) Bipolar disorder ( 31043756) Blood protein levels ( 28240269) Intracranial aneurysm ( 30823506) Platelet distribution width ( 27863252)
Interacting Genes		5 interacting genes: CUL4A DDB1 IRS1 STMN4 TUBB3	23 interacting genes: CAND1 CDKN1B CENPA CHEK1 COMMD1 DCAF6 DCUN1D4 DDB1 DDB2 ERCC8 GPS1 H1-2 H3C1 HOXA9 PHIP RBX1 RNF7 SALL2 SENP8 SKP2 TUBG1 UBC UBE2E3
Entrez ID		55023	8451
HPRD ID		10152	07218
Ensembl ID		ENSG00000146247	ENSG00000139842
Uniprot IDs		Q8WWQ0	A0A0A0MR50 Q13619
PDB IDs		3MB3 5ENB 5ENC 5ENE 5ENF 5ENH 5ENI 5ENJ	2HYE 4A0K
Enriched GO Terms of Interacting Partners?
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