PPM1A and CACNA1C

  • Number of citations of the paper that reports this interaction (PubMedID 15728831)
  • 9
  • Data Source:
  • HPRD (in vivo, in vitro)

PPM1A

CACNA1C

Description protein phosphatase, Mg2+/Mn2+ dependent 1A calcium voltage-gated channel subunit alpha1 C
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Allergic rhinitis ( 22036096)
  • Blond vs. brown/black hair color ( 30531825)
  • Chronotype ( 30696823)
  • Diastolic blood pressure ( 30224653)
  • Hair color ( 29662168)
  • Hip circumference adjusted for BMI ( 25673412)
  • Menarche (age at onset) ( 27182965)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • Acoustic startle blink response ( 25387708)
  • Adventurousness ( 30643258)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Aortic root size ( 28394258)
  • Atypical femoral fracture in phosphonate treatment ( 31006051)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Bipolar disorder ( 18711365 31043756 28072414 20351715)
  • Bipolar disorder or major depressive disorder ( 20351715)
  • Bipolar I disorder ( 31043756)
  • Broad depression or bipolar disorder ( 30626913)
  • Broad depression or schizophrenia ( 30626913)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Diastolic blood pressure ( 30224653)
  • Exploratory eye movement dysfunction in schizophrenia (cognitive search score) ( 26242244)
  • Fractional exhaled nitric oxide (childhood) ( 24315451)
  • General risk tolerance (MTAG) ( 30643258)
  • Heel bone mineral density ( 30598549 28869591)
  • Hematocrit ( 27863252)
  • Hemoglobin concentration ( 27863252)
  • Lumbar spine bone mineral density (integral) ( 27476799)
  • Lumbar spine bone mineral density (trabecular) ( 27476799)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Perceived intensity of aspartame ( 31005972)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale) ( 28525603)
  • Psychosis proneness (hypomanic personality scale) ( 28525603)
  • Red blood cell count ( 29403010 27863252)
  • Red blood cell traits ( 23222517)
  • Response to olanzapine in schizophrenia ( 29503163)
  • Resting heart rate ( 29769521 27798624)
  • Schizophrenia ( 28991256 25056061 21926974 29483656 22688191 30285260 23974872)
  • Schizophrenia or bipolar disorder ( 24280982)
  • Sensorimotor dexterity ( 31596458)
  • Short-term memory (digit-span task) ( 30741946)
  • Sleep quality ( 23728906)
  • Warfarin maintenance dose ( 18535201)
Interacting Genes 37 interacting genes: AATK AKT1 ALK CACNA1A CACNA1B CACNA1C CDC42BPA CDC42BPB CTNNB1 DVL1 DVL2 DVL3 EEF2 EGFR ERBB2 ERBB3 ERBB4 FGFR2 GRM3 HSPB1 IGF1R KDR LMTK2 MSN NR4A1 PAK1 PAK2 PIK3R1 PLK3 PRKAA1 PRKCA PRKCD PTK7 ROR2 RPLP0 SMAD2 SMAD3 11 interacting genes: CABP1 CACNB3 COPS5 GNB1 HDAC4 PCBD1 PPM1A PRKACA RIMS1 RYR2 SRI
Entrez ID 5494 775
HPRD ID 16199 00246
Ensembl ID ENSG00000100614 ENSG00000151067
Uniprot IDs A0A024R6A5 B2R8E4 P35813 A0A0A0MR67 A0A0A0MSA1 F5H522 Q13936 Q59GU3 Q5V9X9
PDB IDs 1A6Q 3FXJ 3FXK 3FXL 3FXM 3FXO 4RA2 4RAF 4RAG 6B67 1T0J 2BE6 2F3Y 2F3Z 2LQC 3G43 3OXQ 5V2P 5V2Q 6C0A 6DAD 6DAE 6DAF
Enriched GO Terms of Interacting Partners?
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