RASIP1 and LDB2

Number of citations of the paper that reports this interaction (PubMedID 18330356)
6

Data Source:
BioGRID (two hybrid)

		RASIP1	LDB2
Description		Ras interacting protein 1	LIM domain binding 2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Stack Cell-cell Junction Protein-containing Complex Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Transcription Factor Complex Nucleolus Plasma Membrane Cell Leading Edge
	Molecular Function	Protein Binding Protein Homodimerization Activity GTPase Binding	RNA Polymerase II Activating Transcription Factor Binding Transcription Coregulator Activity Protein Binding Enzyme Binding LIM Domain Binding
	Biological Process	Angiogenesis Vasculogenesis Signal Transduction Negative Regulation Of Autophagy Positive Regulation Of Integrin Activation Negative Regulation Of Rho Protein Signal Transduction Regulation Of GTPase Activity Branching Morphogenesis Of An Epithelial Tube Negative Regulation Of Membrane Permeability Negative Regulation Of Rho-dependent Protein Serine/threonine Kinase Activity	Negative Regulation Of Transcription By RNA Polymerase II Hair Follicle Development Multicellular Organism Development Epithelial Structure Maintenance Regulation Of Cell Migration Somatic Stem Cell Population Maintenance Regulation Of Kinase Activity Positive Regulation Of Cellular Component Biogenesis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Alcohol consumption ( 31358974) Alcohol use disorder (total score) ( 30336701) Bipolar disorder ( 21926972) Blood protein levels in cardiovascular risk ( 28369058) C-reactive protein levels or LDL-cholesterol levels (pleiotropy) ( 27286809) Crohn's disease ( 28067908 21102463) Dietary macronutrient intake ( 23372041) Estimated glomerular filtration rate ( 31015462) Inflammatory bowel disease ( 28067908) Inflammatory skin disease ( 25574825) Mean platelet volume ( 27863252) Retinal vascular caliber ( 21060863) Urinary albumin-to-creatinine ratio ( 31511532) Vitamin B levels in ischemic stroke ( 25147783) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)	Change in LVEF in response to paclitaxel and trastuzumab in HER2+ breast cancer ( 28763429) Number of sexual partners ( 30643258) QT interval ( 23534349) Rhegmatogenous retinal detachment ( 23585552) Systemic juvenile idiopathic arthritis ( 27927641) Waist circumference ( 28552196)
Interacting Genes		8 interacting genes: ARFGAP1 HRAS LDB2 MRAS RAP1A RAP2A RRAS RRAS2	12 interacting genes: ISL1 LHX4 LHX9 LMO3 LMO4 RASIP1 RILP RLIM SSBP2 SSBP3 SSBP4 TSNAX
Entrez ID		54922	9079
HPRD ID		15214	16022
Ensembl ID		ENSG00000105538	ENSG00000169744
Uniprot IDs		Q5U651 Q7L251 Q8IUR2	B7Z6D0 E9PFI4 G5E9Y7 O43679
PDB IDs		5KHO 5KHQ
Enriched GO Terms of Interacting Partners?
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