PRR13 and SRI

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PRR13	SRI
Description		proline rich 13	sorcin
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol	Cell Nucleoplasm Cytoplasm Mitochondrion Endoplasmic Reticulum Membrane Smooth Endoplasmic Reticulum Cytosol Membrane Sarcoplasmic Reticulum Z Disc T-tubule Sarcoplasmic Reticulum Membrane Chromaffin Granule Membrane Axon Terminus Dendritic Spine Neck Extracellular Exosome
	Molecular Function	Protein Binding	Protease Binding Signaling Receptor Binding Calcium Channel Regulator Activity Calcium Ion Binding Protein Binding Ion Channel Binding Protein Heterodimerization Activity Repressing Transcription Factor Binding
	Biological Process		Action Potential Calcium Ion Transport Intracellular Sequestering Of Iron Ion Regulation Of Striated Muscle Contraction Signal Transduction Heart Development Muscle Organ Development Regulation Of Heart Contraction Negative Regulation Of Heart Rate Regulation Of Cell Communication By Electrical Coupling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Cytoplasmic Sequestering Of Transcription Factor Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Calcium Ion Transport Negative Regulation Of Cardiac Muscle Contraction Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Cardiac Muscle Cell Contraction Regulation Of Relaxation Of Muscle Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Negative Regulation Of Transcription Regulatory Region DNA Binding
Pathways			Stimuli-sensing channels Reduction of cytosolic Ca++ levels Sodium/Calcium exchangers Ion homeostasis Ion transport by P-type ATPases
Drugs			Calcium Citrate Calcium Phosphate
Diseases
GWAS		Granulocyte percentage of myeloid white cells ( 27863252) Monocyte percentage of white cells ( 27863252)
Interacting Genes		24 interacting genes: BAIAP2 EWSR1 FAM133A GPAA1 KLHL12 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP4-12 LGALS3 LNX1 PEX5 PLSCR1 PPIA PSMA3 PSME3 RP9P RTN4 SDCBP SDCBP2 SRI TNFAIP8 VAC14 ZCCHC10	19 interacting genes: ALG2 ANXA11 ANXA7 CACNA1C CACNA1S CALCOCO2 GCA MTNR1A NRAS PDE4C PRR13 PSEN2 RYR2 SHBG SMAD2 SNCA SRPK2 STAT3 TCF12
Entrez ID		54458	6717
HPRD ID		13211	01680
Ensembl ID		ENSG00000205352	ENSG00000075142
Uniprot IDs		A0A024RB45 Q9NZ81	B4DHQ6 C9J0K6 P30626
PDB IDs			1JUO 2JC2 4U8D 4UPG 4USL 5MRA
Enriched GO Terms of Interacting Partners?
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