NLGN3 and UQCRC1

Number of citations of the paper that reports this interaction (PubMedID 25464930)
5

Data Source:
BioGRID (two hybrid)

		NLGN3	UQCRC1
Description		neuroligin 3	ubiquinol-cytochrome c reductase core protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Cell Junction Endocytic Vesicle Synapse Excitatory Synapse Spanning Component Of Membrane Presynapse Symmetric, GABA-ergic, Inhibitory Synapse Asymmetric, Glutamatergic, Excitatory Synapse Integral Component Of Postsynaptic Membrane	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Mitochondrial Respiratory Chain Complex III Cytosol
	Molecular Function	Protein Binding Signaling Receptor Activity Neurexin Family Protein Binding Cell Adhesion Molecule Binding Scaffold Protein Binding	Ubiquinol-cytochrome-c Reductase Activity Ubiquitin Protein Ligase Binding Protein-containing Complex Binding Metal Ion Binding
	Biological Process	Regulation Of Respiratory Gaseous Exchange By Neurological System Process Receptor-mediated Endocytosis Neuron Cell-cell Adhesion Chemical Synaptic Transmission Synapse Assembly Learning Visual Learning Adult Behavior Social Behavior Synaptic Vesicle Endocytosis Axon Extension Oligodendrocyte Differentiation Modulation Of Chemical Synaptic Transmission Synapse Organization Positive Regulation Of Synapse Assembly Positive Regulation Of Synaptic Transmission, Glutamatergic Rhythmic Synaptic Transmission Excitatory Postsynaptic Potential Inhibitory Postsynaptic Potential Long-term Synaptic Potentiation Negative Regulation Of Dendritic Spine Morphogenesis Vocalization Behavior Negative Regulation Of Excitatory Postsynaptic Potential Postsynaptic Membrane Assembly Presynaptic Membrane Assembly Presynapse Assembly Regulation Of Long-term Synaptic Potentiation Regulation Of NMDA Receptor Activity Regulation Of Terminal Button Organization Positive Regulation Of Excitatory Postsynaptic Potential Positive Regulation Of Synaptic Vesicle Clustering Positive Regulation Of AMPA Receptor Activity	Oxidative Phosphorylation Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Aerobic Respiration Response To Activity Response To Alkaloid Oxidation-reduction Process
Pathways		Neurexins and neuroligins Neurexins and neuroligins	Respiratory electron transport
Drugs			2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol Myxothiazol 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE FAMOXADONE METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-NONYL-4-HYDROXYQUINOLINE N-OXIDE UBIQUINONE-2
Diseases
GWAS		Prostate cancer ( 25217961)	Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Metabolite levels ( 23823483) Ulcerative colitis ( 28067908)
Interacting Genes		56 interacting genes: ALPP AP2A2 ATF4 C1orf122 C1QA CCAR2 CGB3 CTSD DLG2 DLG3 DLG4 DPEP2 EBPL EFS FANCG FBLN1 FHOD1 FKBP1A FLNA GDF15 GUK1 HID1 ITPRIP LGALS1 MAN2C1 MAP1S MEOX2 MIEN1 NFATC4 NRDC NRXN1 NRXN2 NRXN3 OAZ1 OR1F12 PDZD11 PKIB PLB1 PLCB4 PRDX2 PSAP PSG1 PSG11 PSG3 PSG4 PSG5 QARS1 SPAG5 SPINT1 SSR4 TNNT3 TRIM33 TXNIP UBQLN1 UBXN6 UQCRC1	8 interacting genes: CYCS GPX1 HNRNPD KRAS NLGN3 RTN4 TRIM63 UQCRC2
Entrez ID		54413	7384
HPRD ID		02275	01875
Ensembl ID		ENSG00000196338	ENSG00000010256
Uniprot IDs		B7Z3P8 Q4G160 Q6MZK0 Q9NZ94 X5D2P6 X5D7L6 X5DNV3	P31930
PDB IDs			5XTE 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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