TRIM34 and TRIM5

Number of citations of the paper that reports this interaction (PubMedID 16828831)
68

Data Source:
BioGRID (two hybrid, two hybrid)

		TRIM34	TRIM5
Description		tripartite motif containing 34	tripartite motif containing 5
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol	P-body Nucleus Cytoplasm Cytosol Omegasome
	Molecular Function	Molecular_function Zinc Ion Binding Identical Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Protein Kinase Binding Protein Binding, Bridging Pattern Recognition Receptor Activity Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Positive Regulation Of DNA-binding Transcription Factor Activity Defense Response To Virus Interferon-gamma-mediated Signaling Pathway	Activation Of Innate Immune Response Autophagy Viral Process Regulation Of Lipopolysaccharide-mediated Signaling Pathway Regulation Of Protein Localization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of MAPK Cascade Innate Immune Response Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Protein K63-linked Ubiquitination Negative Regulation Of Viral Release From Host Cell
Pathways		Interferon gamma signaling	Interferon gamma signaling
Drugs
Diseases
GWAS			Coronary artery disease ( 29212778) DNA methylation (variation) ( 23725790) Mean platelet volume ( 27863252) Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828) Platelet count ( 29403010) Serum alkaline phosphatase levels ( 29403010)
Interacting Genes		7 interacting genes: BIRC2 MKRN3 MNAT1 TRIM5 UBE2K UBE2U USP2	38 interacting genes: BTBD1 BTBD2 EWSR1 LGALS8 LZTR1 MKRN3 MNAT1 OTUB2 OTUD6A PCBD1 PIAS1 PRKCG PSMC2 RUNX1 TNFAIP3 TRIM21 TRIM32 TRIM34 TRIM35 TRIM6 UBB UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2H UBE2K UBE2N UBE2U UBE2V1 UBE2V2 UBE2W USP15 USP2 USP21 USP39 USP5
Entrez ID		53840	85363
HPRD ID		16141	07004
Ensembl ID		ENSG00000258659	ENSG00000132256
Uniprot IDs		Q9BYJ4	Q9C035
PDB IDs		2EGP	2ECV 2YRG
Enriched GO Terms of Interacting Partners?
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