FXYD3 and FBXL12

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FXYD3	FBXL12
Description		FXYD domain containing ion transport regulator 3	F-box and leucine rich repeat protein 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome	Nucleus Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	Chloride Channel Activity Sodium Channel Regulator Activity Ion Channel Regulator Activity	Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Potassium Ion Transport Sodium Ion Transport Chloride Transport Ion Transmembrane Transport Chloride Transmembrane Transport Regulation Of Cardiac Conduction Regulation Of Sodium Ion Transmembrane Transporter Activity	G2/M Transition Of Mitotic Cell Cycle Protein Polyubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Regulation Of Cell Cycle
Pathways		Ion homeostasis Ion transport by P-type ATPases	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Pursuit maintenance gain ( 29064472)
Interacting Genes		8 interacting genes: CREB3 CREB3L1 FBXL12 LMNA MAPK6 NR4A1 NUDT3 SERBP1	22 interacting genes: A2M ALDH3A1 APOE CDC37 CDKN1C DOCK8 ECSIT FXYD3 LNX1 MARCHF2 MAST1 PSEN1 PSEN2 PSME3 RNF32 SHFL SMAD1 TGFBR1 UBE2D3 ZNF44 ZNF562 ZNF823
Entrez ID		5349	54850
HPRD ID		05410	12363
Ensembl ID		ENSG00000089356	ENSG00000127452
Uniprot IDs		Q14802	Q9NXK8
PDB IDs
Enriched GO Terms of Interacting Partners?
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