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CLIC5 and EZR
Number of citations of the paper that reports this interaction (PubMedID
10793131
)
43
Data Source:
HPRD
(in vitro)
CLIC5
EZR
Description
chloride intracellular channel 5
ezrin
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Apparatus
Microtubule Organizing Center
Cell Cortex
Actin Cytoskeleton
Apical Plasma Membrane
Chloride Channel Complex
Extracellular Exosome
Fibrillar Center
Ruffle
Immunological Synapse
Uropod
Extracellular Space
Cell
Cytoplasm
Endosome
Cytosol
Actin Filament
Plasma Membrane
Microvillus
Brush Border
Focal Adhesion
Actin Cytoskeleton
Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Extrinsic Component Of Membrane
Filopodium
T-tubule
Cortical Cytoskeleton
Microvillus Membrane
Vesicle
Ruffle Membrane
Protein-containing Complex
Ciliary Basal Body
Cell Projection
Cell Body
Microspike
Plasma Membrane Raft
Apical Part Of Cell
Perinuclear Region Of Cytoplasm
Cell Tip
Extracellular Exosome
Invadopodium
Cell Periphery
Astrocyte Projection
Schwann Cell Microvillus
Cytoplasmic Side Of Apical Plasma Membrane
Molecular Function
Voltage-gated Ion Channel Activity
Chloride Channel Activity
Protein Binding
RNA Binding
Actin Binding
Protein Binding
Microtubule Binding
Protein C-terminus Binding
Protein Domain Specific Binding
Protein Kinase A Catalytic Subunit Binding
Protein Kinase A Regulatory Subunit Binding
Identical Protein Binding
S100 Protein Binding
Cadherin Binding
Cell Adhesion Molecule Binding
Actin Filament Binding
Protein Kinase A Binding
ATPase Binding
Disordered Domain Specific Binding
Biological Process
Chloride Transport
Female Pregnancy
Visual Perception
Sensory Perception Of Sound
Regulation Of Ion Transmembrane Transport
Response To Stimulus
Chloride Transmembrane Transport
Negative Regulation Of Transcription By RNA Polymerase II
Intestinal D-glucose Absorption
Sphingosine-1-phosphate Receptor Signaling Pathway
Cytoskeletal Anchoring At Plasma Membrane
Leukocyte Cell-cell Adhesion
Axon Guidance
Regulation Of Cell Shape
Regulation Of Cell Size
Positive Regulation Of Gene Expression
Protein Kinase A Signaling
Gland Morphogenesis
Membrane To Membrane Docking
Microvillus Assembly
Astral Microtubule Organization
Actin Cytoskeleton Reorganization
Receptor Internalization
Regulation Of Microvillus Length
Regulation Of Actin Cytoskeleton Organization
Cellular Protein-containing Complex Localization
Positive Regulation Of Multicellular Organism Growth
Cortical Microtubule Organization
Establishment Of Epithelial Cell Apical/basal Polarity
Filopodium Assembly
Phosphatidylinositol-mediated Signaling
Positive Regulation Of Protein Secretion
Negative Regulation Of T Cell Receptor Signaling Pathway
Actin Filament Bundle Assembly
Establishment Of Centrosome Localization
Establishment Of Endothelial Barrier
Negative Regulation Of ERK1 And ERK2 Cascade
Cellular Response To CAMP
Protein Localization To Plasma Membrane
Protein Localization To Cell Cortex
Negative Regulation Of Interleukin-2 Secretion
Regulation Of NIK/NF-kappaB Signaling
Regulation Of Organelle Assembly
Terminal Web Assembly
Positive Regulation Of Protein Localization To Early Endosome
Positive Regulation Of Protein Localization To Plasma Membrane
Positive Regulation Of Cellular Protein Catabolic Process
Negative Regulation Of P38MAPK Cascade
Positive Regulation Of Early Endosome To Late Endosome Transport
Pathways
Netrin-1 signaling
Recycling pathway of L1
Recycling pathway of L1
Drugs
Diseases
GWAS
Blond vs. brown/black hair color (
30531825
)
Blood protein levels (
30072576
29875488
)
Cerebrospinal AB1-42 levels in normal cognition (
29274321
)
Heel bone mineral density (
30598549
)
Intraocular pressure (
29785010
)
Itch intensity from mosquito bite (
28199695
)
Mosquito bite size (
28199695
)
Periodontal microbiota (
22699663
)
Bladder cancer (smoking interaction) (
24662972
)
Blond vs. brown/black hair color (
30531825
)
Brown vs. black hair color (
30531825
)
Hair color (
29662168
)
Interacting Genes
6 interacting genes:
ACTA1
ACTN1
EZR
GSN
IQGAP1
SRPK1
51 interacting genes:
ACTB
ACTC1
ADORA2B
ADRA1B
ARF6
ARHGDIB
CD44
CDH1
CDK5
CFTR
CLIC5
CTNNB1
DLG1
EGFR
FAS
FASLG
GZMM
ICAM1
ICAM2
ICAM3
IQGAP1
L1CAM
LCK
MDM2
MME
MPP3
MSN
NF2
PALLD
PIK3R1
PRKAR2A
PRKCA
PTK2
PTPRC
RDX
ROCK1
S100P
SCYL3
SDC2
SELL
SELP
SLC9A3R1
SLC9A3R2
SPN
TBC1D10A
TMEM8B
TSC1
VCAM1
VPS11
WFDC1
WWOX
Entrez ID
53405
7430
HPRD ID
06292
00475
Ensembl ID
ENSG00000112782
ENSG00000092820
Uniprot IDs
Q49AE1
Q53G01
Q9NZA1
P15311
PDB IDs
1NI2
4RM8
4RM9
4RMA
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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