PLG and THBS1

  • Number of citations of the paper that reports this interaction (PubMedID 2522013)
  • 4
  • Data Source:
  • HPRD (in vitro)

PLG

THBS1

Description plasminogen thrombospondin 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Aging ( 22773346)
  • Blood protein levels ( 30072576 29875488 28240269)
  • Body mass index ( 26426971)
  • Body mass index (age>50) ( 26426971)
  • Body mass index x sex x age interaction (4df test) ( 26426971)
  • Childhood ear infection ( 27182965 28928442)
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
  • Coronary artery disease ( 26343387)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • End stage renal disease x APOL1 genotype interaction ( 29885931)
  • Giant cell arteritis ( 28041642)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels in current drinkers ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Lipoprotein (a) levels ( 26377243)
  • Lp (a) levels ( 21900290)
  • Myocardial infarction ( 26343387)
  • Plasma plasminogen levels ( 25208887)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Logical memory (immediate recall) in normal cognition ( 29274321)
  • Urate levels ( 31578528)
Interacting Genes 60 interacting genes: ACTB AMOT ANXA2 APOH ATP5F1B C7 CDCP1 CHGA CLEC3B CP CPB2 CXCL2 CYFIP2 ENO1 EP300 F10 F2R F2RL1 F3 FN1 HMGB1 HRG HSPA1A HSPB1 HSPD1 IGF2 IGFBP3 KLK3 KNG1 LAMA1 LAMA3 MAPK14 MEP1A MMP3 MMP7 MMP9 NGF PAPPA PCOLCE PLAT PLAU PRDX4 PRNP RAP2A RBBP6 RUVBL1 S100A10 SERPINB13 SERPINB6 SERPINC1 SERPINE1 SERPINF2 SERPING1 SERPINI1 SMAD3 SMAD4 SPARC TFPI2 THBS1 YTHDC1 40 interacting genes: CALCR CALR CD36 CD47 CFH COL1A1 COL2A1 COL3A1 COL4A1 COL5A1 COL7A1 CORO1A CTSG DCN DHFR ELANE F2 FGA FGF2 FN1 HRG IGFBP5 ITGB3 JAG1 KNG1 LAMB3 LRP1 LRP2 LRP5 MMP2 MMP9 MTDH PDGFB PLG SCARB2 SPARC TFPI TGFB1 TNFAIP6 TNFRSF11B
Entrez ID 5340 7057
HPRD ID 01417 01765
Ensembl ID ENSG00000122194 ENSG00000137801
Uniprot IDs P00747 Q5TEH5 P07996
PDB IDs 1B2I 1BML 1BUI 1CEA 1CEB 1DDJ 1HPJ 1HPK 1I5K 1KI0 1KRN 1L4D 1L4Z 1PK4 1PKR 1PMK 1QRZ 1RJX 2DOH 2DOI 2KNF 2L0S 2PK4 3UIR 4A5T 4CIK 4DCB 4DUR 4DUU 5HPG 5UGD 5UGG 6D3X 6D3Y 6D3Z 6D40 6OG4 6OQJ 6OQK 1LSL 1UX6 1Z78 1ZA4 2ERF 2ES3 2OUH 2OUJ 3R6B 5FOE
Enriched GO Terms of Interacting Partners?
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