ATP6V0C and MSR1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ATP6V0C	MSR1
Description		ATPase H+ transporting V0 subunit c	macrophage scavenger receptor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Lysosomal Membrane Plasma Membrane Focal Adhesion Endosome Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain Azurophil Granule Membrane Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane	Collagen Trimer Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Endocytic Vesicle Membrane Low-density Lipoprotein Particle
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism	Amyloid-beta Binding Scavenger Receptor Activity Protein Binding Low-density Lipoprotein Particle Binding Cargo Receptor Activity
	Biological Process	Insulin Receptor Signaling Pathway Viral Process Regulation Of Macroautophagy Positive Regulation Of Wnt Signaling Pathway Transferrin Transport Ion Transmembrane Transport Neutrophil Degranulation Phagosome Acidification Proton Transmembrane Transport	Receptor-mediated Endocytosis Phagocytosis, Engulfment Negative Regulation Of Gene Expression Positive Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Cholesterol Storage Cholesterol Transport Plasma Lipoprotein Particle Clearance Amyloid-beta Clearance
Pathways		ROS and RNS production in phagocytes Neutrophil degranulation Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport	Scavenging by Class A Receptors Scavenging by Class A Receptors
Drugs
Diseases
GWAS			Alcohol dependence ( 26365420) Blood protein levels ( 23696881) Hip circumference adjusted for BMI ( 28552196) Neurological blood protein biomarker levels ( 31320639)
Interacting Genes		11 interacting genes: ARF6 CERS2 CLIC1 CREB3 EDA LMNA MARK3 MDFI MSR1 PSMA3 SMIM3	6 interacting genes: ATP6V0C HSPA1A LEPROTL1 MALL NKG7 SEC22A
Entrez ID		527	4481
HPRD ID		00162	01092
Ensembl ID		ENSG00000185883	ENSG00000038945
Uniprot IDs		P27449	P21757
PDB IDs
Enriched GO Terms of Interacting Partners?
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