MSR1 and ATP6V0C

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MSR1	ATP6V0C
Description		macrophage scavenger receptor 1	ATPase H+ transporting V0 subunit c
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Collagen Trimer Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Endocytic Vesicle Membrane Low-density Lipoprotein Particle	Cell Lysosomal Membrane Plasma Membrane Focal Adhesion Endosome Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain Azurophil Granule Membrane Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Amyloid-beta Binding Scavenger Receptor Activity Protein Binding Low-density Lipoprotein Particle Binding Cargo Receptor Activity	Protein Binding Ubiquitin Protein Ligase Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Receptor-mediated Endocytosis Phagocytosis, Engulfment Negative Regulation Of Gene Expression Positive Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Cholesterol Storage Cholesterol Transport Plasma Lipoprotein Particle Clearance Amyloid-beta Clearance	Insulin Receptor Signaling Pathway Viral Process Regulation Of Macroautophagy Positive Regulation Of Wnt Signaling Pathway Transferrin Transport Ion Transmembrane Transport Neutrophil Degranulation Phagosome Acidification Proton Transmembrane Transport
Pathways		Scavenging by Class A Receptors Scavenging by Class A Receptors	ROS and RNS production in phagocytes Neutrophil degranulation Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs
Diseases
GWAS		Alcohol dependence ( 26365420) Blood protein levels ( 23696881) Hip circumference adjusted for BMI ( 28552196) Neurological blood protein biomarker levels ( 31320639)
Interacting Genes		6 interacting genes: ATP6V0C HSPA1A LEPROTL1 MALL NKG7 SEC22A	11 interacting genes: ARF6 CERS2 CLIC1 CREB3 EDA LMNA MARK3 MDFI MSR1 PSMA3 SMIM3
Entrez ID		4481	527
HPRD ID		01092	00162
Ensembl ID		ENSG00000038945	ENSG00000185883
Uniprot IDs		P21757	P27449
PDB IDs
Enriched GO Terms of Interacting Partners?
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