SERPINB5 and PPIF

Number of citations of the paper that reports this interaction (PubMedID 16049007)
27

Data Source:
BioGRID (two hybrid)

		SERPINB5	PPIF
Description		serpin family B member 5	peptidylprolyl isomerase F
Image
GO Annotations	Cellular Component	Extracellular Space Cytoplasm	Mitochondrion Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Permeability Transition Pore Complex Mitochondrial Matrix Membrane
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Protein Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Unfolded Protein Binding
	Biological Process	Morphogenesis Of An Epithelium Negative Regulation Of Endopeptidase Activity Extracellular Matrix Organization Regulation Of Epithelial Cell Proliferation Prostate Gland Morphogenesis	Protein Peptidyl-prolyl Isomerization Response To Ischemia Apoptotic Mitochondrial Changes Regulation Of Proton-transporting ATPase Activity, Rotational Mechanism Regulation Of Necrotic Cell Death Negative Regulation Of ATPase Activity Protein Refolding Negative Regulation Of Apoptotic Process Regulation Of Mitochondrial Membrane Permeability Necroptotic Process Cellular Response To Hydrogen Peroxide Cellular Response To Arsenic-containing Substance Cellular Response To Calcium Ion Positive Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Oxidative Phosphorylation Regulation Of Mitochondrial Membrane Permeability Involved In Programmed Necrotic Cell Death Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Negative Regulation Of Oxidative Phosphorylation Uncoupler Activity Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs		S,S-(2-Hydroxyethyl)Thiocysteine	Cyclosporine L-Proline 1-Methoxy-2-[2-(2-Methoxy-Ethoxy]-Ethane 7-AMINO-4-METHYL-CHROMEN-2-ONE
Diseases
GWAS		Adverse response to chemotherapy in breast cancer (alopecia) (anti-microtubule) ( 24025145)	Blood protein levels ( 30072576) Height ( 20881960 31562340) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Metabolite levels ( 23823483)
Interacting Genes		26 interacting genes: AKT1 ATIC BASP1 BCAR3 CASP8 COL1A2 EEF1A1 ESR1 GOLGA4 GSTO1 HDAC1 HSP90AA1 HSP90AB1 HSPA5 KRAS LRRFIP1 MDH1 MT1H PALB2 PPIF SMAD4 STK11 TBP TKT UCHL5 XRCC3	6 interacting genes: ABI2 BANP CMTM5 SERPINB5 SLC25A4 VDAC1
Entrez ID		5268	10105
HPRD ID		01111	06839
Ensembl ID		ENSG00000206075	ENSG00000108179
Uniprot IDs		A0A024R2B6 P36952	A0A024QZS4 P30405
PDB IDs		1WZ9 1XQG 1XQJ 1XU8	2BIT 2BIU 2Z6W 3QYU 3R49 3R4G 3R54 3R56 3R57 3R59 3RCF 3RCG 3RCI 3RCK 3RCL 3RD9 3RDA 3RDB 3RDC 4J58 4J59 4J5A 4J5B 4J5C 4J5D 4J5E 4O8H 4O8I 4XNC 4ZSC 4ZSD 5A0E 5CBT 5CBU 5CBV 5CBW 5CCN 5CCQ 5CCR 5CCS 5NWO 6GJX 6R8L 6R8O 6R8W 6R9S 6R9U 6R9X 6RA1
Enriched GO Terms of Interacting Partners?
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