PHYH and ACSL6

Number of citations of the paper that reports this interaction (PubMedID 12767919)
5

Data Source:
HPRD (in vitro)

		PHYH	ACSL6
Description		phytanoyl-CoA 2-hydroxylase	acyl-CoA synthetase long chain family member 6
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Peroxisome Peroxisomal Matrix Cytosol	Mitochondrial Outer Membrane Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Ferrous Iron Binding Carboxylic Acid Binding L-ascorbic Acid Binding Cofactor Binding Phytanoyl-CoA Dioxygenase Activity	Acyl-CoA Ligase Activity Long-chain Fatty Acid-CoA Ligase Activity ATP Binding Protein Homodimerization Activity Arachidonate-CoA Ligase Activity Decanoate-CoA Ligase Activity
	Biological Process	Fatty Acid Alpha-oxidation 2-oxoglutarate Metabolic Process Protein Targeting To Peroxisome Isoprenoid Metabolic Process 2-oxobutyrate Catabolic Process Methyl-branched Fatty Acid Metabolic Process	Long-chain Fatty Acid Metabolic Process Acyl-CoA Metabolic Process Long-chain Fatty-acyl-CoA Biosynthetic Process
Pathways		Alpha-oxidation of phytanate Peroxisomal protein import Peroxisomal protein import TYSND1 cleaves peroxisomal proteins	Synthesis of very long-chain fatty acyl-CoAs
Drugs		Antihemophilic factor, human recombinant Vitamin C
Diseases		Refsum disease; Heredopathia atactica polyneuritiformis
GWAS			Alzheimer's disease in APOE e4- carriers ( 25778476) Crohn's disease ( 28067908 22412388) Inflammatory bowel disease ( 28067908 23128233) Perceived unattractiveness to mosquitoes ( 28199695) Ulcerative colitis ( 28067908)
Interacting Genes		10 interacting genes: ACSL6 APP F8 FAM9B FKBP4 MAGEA11 PEX7 PHYHIP SIRPA TOM1L1	1 interacting genes: PHYH
Entrez ID		5264	23305
HPRD ID		03609	09190
Ensembl ID		ENSG00000107537	ENSG00000164398
Uniprot IDs		O14832	B2RB13 B4DFW3 Q9UKU0
PDB IDs		2A1X
Enriched GO Terms of Interacting Partners?
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