PHKB and HNRNPC

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PHKB	HNRNPC
Description		phosphorylase kinase regulatory subunit beta	heterogeneous nuclear ribonucleoprotein C
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Phosphorylase Kinase Complex	Nuclear Chromatin Extracellular Region Nucleus Nucleoplasm Spliceosomal Complex Telomerase Holoenzyme Complex Cytosol Actin Cytoskeleton Membrane Protein-containing Complex Extracellular Exosome Catalytic Step 2 Spliceosome
	Molecular Function	Phosphorylase Kinase Activity Protein Binding Calmodulin Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Poly(U) RNA Binding Nucleosomal DNA Binding Identical Protein Binding Telomerase RNA Binding N6-methyladenosine-containing RNA Binding
	Biological Process	Glycogen Metabolic Process Glycogen Catabolic Process Generation Of Precursor Metabolites And Energy Protein Phosphorylation	MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Splicing RNA Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase ATP-dependent Chromatin Remodeling 3'-UTR-mediated MRNA Stabilization
Pathways		Glycogen breakdown (glycogenolysis) Glycogen breakdown (glycogenolysis)	SUMOylation of RNA binding proteins mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases		Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS			Bipolar disorder ( 31043756 21738484) Height ( 31562340)
Interacting Genes		5 interacting genes: C20orf27 CALM1 CAMK2B HNRNPC TLE5	51 interacting genes: AP1M1 BARD1 BRCA1 BRCA2 BRIP1 BTRC CCDC85B CDKN2A CELF1 CSNK1A1 CSNK2A1 CSNK2A2 DHX9 EPS8 ERG ESR1 FAS FXR2 GRB2 IL7R KHDRBS3 KPNA2 KPNA3 KPNA4 KRAS LMO2 LMO3 PALB2 PDGFB PHKB PIN1 PJA1 PRKDC PTBP2 RAD51 RALY RALYL RBM41 SDCBP SF3B2 SMARCD1 SREK1 SRPK2 SUMO1 SUMO1P1 TRAF3 UBE2I YWHAE YWHAQ ZFYVE26 ZNF581
Entrez ID		5257	3183
HPRD ID		01407	01243
Ensembl ID		ENSG00000102893	ENSG00000092199
Uniprot IDs		Q93100	P07910
PDB IDs			1TXP 1WF2 2MXY 2MZ1 3LN4
Enriched GO Terms of Interacting Partners?
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