PGK1 and SUMO4

Number of citations of the paper that reports this interaction (PubMedID 16236267)
27

Data Source:
HPRD (in vivo)

		PGK1	SUMO4
Description		phosphoglycerate kinase 1	small ubiquitin like modifier 4
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytosol Membrane Membrane Raft Extracellular Exosome
	Molecular Function	Phosphoglycerate Kinase Activity Protein Binding ATP Binding ADP Binding Protein-disulfide Reductase Activity
	Biological Process	Gluconeogenesis Glycolytic Process Phosphorylation Negative Regulation Of Angiogenesis Epithelial Cell Differentiation Plasminogen Activation Canonical Glycolysis Cellular Response To Hypoxia Positive Regulation Of Oxidative Phosphorylation
Pathways		Glycolysis Gluconeogenesis Manipulation of host energy metabolism
Drugs		Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate 3-phospho-D-glyceric acid Copper Artenimol
Diseases		Anemia due to disorders of glycolytic enzymes, including: Hexokinase (HK) deficiency; Phosphoglycerate kinase 1 (PGK1) deficiency; Triose-phosphate isomerase (TPI) deficiency; Glucose phosphate isomerase (GPI) deficiency; Bisphosphoglycerate mutase (BPGM) deficiency
GWAS			Dupuytren's disease ( 28886342)
Interacting Genes		10 interacting genes: BECN1 DISC1 GAPDH HIF1A HSPH1 NAA10 PCNA RHOU SUMO4 YWHAQ	75 interacting genes: ACADM ACO2 ACTG1 ALDOA ARHGDIA ATP5F1B CALR CAT CCT2 CCT5 CCT6A CCT7 CLIC1 DNAJA1 DNAJB11 EIF3I ENO1 ENO2 FOS G6PD GAPDH GMPS GSTP1 HNRNPD HNRNPF HNRNPH1 HNRNPL HSPA1B HSPA5 HSPA8 HSPA9 HSPD1 IDH1 IDH3A IMPDH2 JUN LDHB LMNA LMNB1 MRPS22 NFKBIA NR3C1 PA2G4 PAFAH1B3 PDIA3 PDIA6 PGK1 PHB PHGDH PITHD1 PPA1 PRDX2 PRDX3 PRDX4 PRDX6 PRPS1 PSMC2 RACK1 RPSA SF3B4 SPINT2 STAT1 STAT3 STIP1 STOML2 STRAP TFAP2A TOP2A TPM3 TUBA1C TXNL1 UBE2V1 VCP VDAC1 ZPR1
Entrez ID		5230	387082
HPRD ID		02412	10584
Ensembl ID		ENSG00000102144	ENSG00000177688
Uniprot IDs		P00558 V9HWF4	Q6EEV6
PDB IDs		2WZB 2WZC 2WZD 2X13 2X14 2X15 2XE6 2XE7 2XE8 2Y3I 2YBE 2ZGV 3C39 3C3A 3C3B 3C3C 3ZOZ 4AXX 4O33 5M1R 5M3U 5M6Z 5MXM 5NP8 5O7D
Enriched GO Terms of Interacting Partners?
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