SIX4 and EYA2

  • Number of citations of the paper that reports this interaction (PubMedID 10490620)
  • 89
  • Data Source:
  • BioGRID (proximity labelling technology, two hybrid)
  • HPRD (in vitro)

SIX4

EYA2

Description SIX homeobox 4 EYA transcriptional coactivator and phosphatase 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Exhaled carbon monoxide levels in smokers with chronic obstructive pulmonary disease ( 29631575)
  • Height ( 31562340)
  • Allergic rhinitis ( 31361310)
  • Brain volume in infants (intracranial brain volume) ( 28763065)
  • Coffee consumption ( 31046077)
  • FEV1 ( 30804560)
  • Heel bone mineral density ( 30598549 28869591)
  • Lung function (FVC) ( 30061609 30804560)
  • Non-del(5q) myelodysplastic syndromes ( 31738830)
  • Peak expiratory flow ( 30804560)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Type 2 diabetes ( 30054458 30297969)
  • Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
Interacting Genes 2 interacting genes: EYA2 EYA3 9 interacting genes: AATK DMRTB1 GNAI2 GNAZ LOX RBPMS ROR2 SIX1 SIX4
Entrez ID 51804 2139
HPRD ID 06960 09041
Ensembl ID ENSG00000100625 ENSG00000064655
Uniprot IDs Q9UIU6 E7ETN2 O00167
PDB IDs 3GEB 3HB0 3HB1 4EGC 5ZMA
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?