ATP8A2 and UIMC1

Number of citations of the paper that reports this interaction (PubMedID 17621610)
72

Data Source:
BioGRID (enzymatic study)

		ATP8A2	UIMC1
Description		ATPase phospholipid transporting 8A2	ubiquitin interaction motif containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Nucleoplasm Endosome Golgi Apparatus Trans-Golgi Network Plasma Membrane Integral Component Of Membrane	Nucleus Nucleoplasm Nuclear Body BRCA1-A Complex
	Molecular Function	Magnesium Ion Binding ATP Binding Aminophospholipid Transmembrane Transporter Activity	Protein Binding Histone Binding Metal Ion Binding K63-linked Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Involuntary Skeletal Muscle Contraction Axonogenesis Aging Negative Regulation Of Cell Proliferation Retina Layer Formation Positive Regulation Of Neuron Projection Development Response To Auditory Stimulus Positive Regulation Of Multicellular Organism Growth Inner Ear Morphogenesis Eating Behavior Skin Development Phospholipid Translocation Neuron Development Neuromuscular Process Controlling Posture Detection Of Light Stimulus Involved In Visual Perception Neurofilament Cytoskeleton Organization Positive Regulation Of Phospholipid Translocation	Double-strand Break Repair Double-strand Break Repair Via Nonhomologous End Joining Response To Ionizing Radiation Protein Deubiquitination Positive Regulation Of DNA Repair Negative Regulation Of Transcription, DNA-templated Histone H2A K63-linked Deubiquitination Signal Transduction Involved In G2 DNA Damage Checkpoint
Pathways		Ion transport by P-type ATPases	Metalloprotease DUBs Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Nonhomologous End-Joining (NHEJ) Processing of DNA double-strand break ends G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Breast milk fatty acid composition (infant genotype effect) ( 29514873) Breast milk fatty acid composition (maternal genotype effect) ( 29514873) Common carotid intima-media thickness ( 29206233) Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer ( 27143689) Eating disorders ( 23568457) Nonsyndromic cleft lip ( 31609978) Nonsyndromic cleft palate ( 31609978)	Activated partial thromboplastin time ( 22703881) Menarche and menopause (age at onset) ( 19448621) Menopause (age at onset) ( 22267201 26414677 29773799) Uterine fibroids ( 31649266) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		1 interacting genes: UIMC1	20 interacting genes: ABRAXAS1 ATP8A2 BRCC3 CEP57 CREBBP DVL2 ECPAS ESR1 FANCG H2AC20 INO80B MDC1 NR6A1 SKIL TP53 UBB UBC USP13 WBP2 ZMYM3
Entrez ID		51761	51720
HPRD ID		05795	11482
Ensembl ID		ENSG00000132932	ENSG00000087206
Uniprot IDs		B7Z880 Q6ZU25 Q9NTI2	A0A024R7R0 Q96RL1
PDB IDs			2MKF 2MKG 2N9E 2RR9
Enriched GO Terms of Interacting Partners?
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