UIMC1 and INO80B

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		UIMC1	INO80B
Description		ubiquitin interaction motif containing 1	INO80 complex subunit B
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body BRCA1-A Complex	Nucleoplasm Nucleolus Ino80 Complex
	Molecular Function	Protein Binding Histone Binding Metal Ion Binding K63-linked Polyubiquitin Modification-dependent Protein Binding	Protein Binding Metal Ion Binding
	Biological Process	Double-strand Break Repair Double-strand Break Repair Via Nonhomologous End Joining Response To Ionizing Radiation Protein Deubiquitination Positive Regulation Of DNA Repair Negative Regulation Of Transcription, DNA-templated Histone H2A K63-linked Deubiquitination Signal Transduction Involved In G2 DNA Damage Checkpoint	DNA Repair DNA Recombination Chromatin Remodeling Protein Deubiquitination
Pathways		Metalloprotease DUBs Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Nonhomologous End-Joining (NHEJ) Processing of DNA double-strand break ends G2/M DNA damage checkpoint	UCH proteinases DNA Damage Recognition in GG-NER
Drugs
Diseases
GWAS		Activated partial thromboplastin time ( 22703881) Menarche and menopause (age at onset) ( 19448621) Menopause (age at onset) ( 22267201 26414677 29773799) Uterine fibroids ( 31649266) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		20 interacting genes: ABRAXAS1 ATP8A2 BRCC3 CEP57 CREBBP DVL2 ECPAS ESR1 FANCG H2AC20 INO80B MDC1 NR6A1 SKIL TP53 UBB UBC USP13 WBP2 ZMYM3	6 interacting genes: CD81 E2F6 IGFBP2 PNMA1 SSX2IP UIMC1
Entrez ID		51720	83444
HPRD ID		11482	17110
Ensembl ID		ENSG00000087206	ENSG00000115274
Uniprot IDs		A0A024R7R0 Q96RL1	Q9C086
PDB IDs		2MKF 2MKG 2N9E 2RR9	6HTS
Enriched GO Terms of Interacting Partners?
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