SYT17 and APTX

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SYT17	APTX
Description		synaptotagmin 17	aprataxin
Image
GO Annotations	Cellular Component	Trans-Golgi Network Plasma Membrane Exocytic Vesicle	Chromatin Nuclear Chromatin Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	SNARE Binding Phosphatidylserine Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Clathrin Binding	Chromatin Binding Damaged DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Double-stranded RNA Binding Protein Binding Phosphoglycolate Phosphatase Activity Mismatched DNA Binding DNA 5'-adenosine Monophosphate Hydrolase Activity Metal Ion Binding Protein N-terminus Binding Phosphoprotein Binding DNA-3'-diphospho-5'-guanosine Diphosphatase Single-strand Break-containing DNA Binding
	Biological Process	Regulation Of Dopamine Secretion Vesicle-mediated Transport Calcium Ion Regulated Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Cellular Response To Calcium Ion Positive Regulation Of Dendrite Extension	Single Strand Break Repair DNA Ligation Double-strand Break Repair Cellular Response To DNA Damage Stimulus Dephosphorylation Regulation Of Protein Stability Response To Hydrogen Peroxide Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways
Drugs
Diseases			Coenzyme Q10 deficiency Ataxia with ocular apraxia (AOA), including: Ataxia telangiectasia (AT); Ataxia telangiectasia like disorder (ATLD); Ataxia oculomotor apraxia type 1 (AOA1); Ataxia oculomotor apraxia type 2 (AOA2)
GWAS		Alcohol dependence ( 21876473) Parkinson's disease ( 27182965) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)	Height ( 28552196) Menopause (age at onset) ( 26414677)
Interacting Genes		17 interacting genes: APP APTX CCDC85B CEP63 CEP70 CHMP4A FAM9B GMCL1 IKZF1 MEOX1 MEOX2 NIF3L1 NINL RUNDC3A SSX2IP TRAF2 TSC22D4	16 interacting genes: CALCOCO1 CEP350 CNTROB HIVEP1 MAPKBP1 MBP PARP1 PICK1 PNMA1 SYT17 TP53 TRIM37 TSPYL2 XRCC1 XRCC4 ZNF639
Entrez ID		51760	54840
HPRD ID		17425	05892
Ensembl ID		ENSG00000103528	ENSG00000137074
Uniprot IDs		H3BN78 H3BRH9 Q9BSW7	Q7Z2E3
PDB IDs		2ENP	3KT9 4NDF 4NDG 4NDH 4NDI 6CVO 6CVP 6CVQ 6CVR 6CVS 6CVT
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?