APTX and CEP350

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		APTX	CEP350
Description		aprataxin	centrosomal protein 350
Image
GO Annotations	Cellular Component	Chromatin Nuclear Chromatin Nucleus Nucleoplasm Nucleolus Cytoplasm	Nucleus Cytoplasm Centrosome Centriole Spindle Membrane Cell Projection
	Molecular Function	Chromatin Binding Damaged DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Double-stranded RNA Binding Protein Binding Phosphoglycolate Phosphatase Activity Mismatched DNA Binding DNA 5'-adenosine Monophosphate Hydrolase Activity Metal Ion Binding Protein N-terminus Binding Phosphoprotein Binding DNA-3'-diphospho-5'-guanosine Diphosphatase Single-strand Break-containing DNA Binding	Protein Binding Microtubule Binding
	Biological Process	Single Strand Break Repair DNA Ligation Double-strand Break Repair Cellular Response To DNA Damage Stimulus Dephosphorylation Regulation Of Protein Stability Response To Hydrogen Peroxide Nucleic Acid Phosphodiester Bond Hydrolysis	Microtubule Anchoring
Pathways
Drugs
Diseases		Coenzyme Q10 deficiency Ataxia with ocular apraxia (AOA), including: Ataxia telangiectasia (AT); Ataxia telangiectasia like disorder (ATLD); Ataxia oculomotor apraxia type 1 (AOA1); Ataxia oculomotor apraxia type 2 (AOA2)
GWAS		Height ( 28552196) Menopause (age at onset) ( 26414677)	Anorexia nervosa ( 23568457) Smoking initiation ( 30617275)
Interacting Genes		16 interacting genes: CALCOCO1 CEP350 CNTROB HIVEP1 MAPKBP1 MBP PARP1 PICK1 PNMA1 SYT17 TP53 TRIM37 TSPYL2 XRCC1 XRCC4 ZNF639	11 interacting genes: ADIPOR1 APH1A APTX CEP19 ID3 NR1H3 PLEKHA5 PPARA PPARD PPARG RSRP1
Entrez ID		54840	9857
HPRD ID		05892	09870
Ensembl ID		ENSG00000137074	ENSG00000135837
Uniprot IDs		Q7Z2E3	Q5VT06
PDB IDs		3KT9 4NDF 4NDG 4NDH 4NDI 6CVO 6CVP 6CVQ 6CVR 6CVS 6CVT	2COZ
Enriched GO Terms of Interacting Partners?
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