CPSF3 and FAM107A

Number of citations of the paper that reports this interaction (PubMedID 28604741)
5

Data Source:
BioGRID (two hybrid)

		CPSF3	FAM107A
Description		cleavage and polyadenylation specific factor 3	family with sequence similarity 107 member A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex	Stress Fiber Nucleus Cytoplasm Focal Adhesion Actin Cytoskeleton Nuclear Speck Ruffle Membrane Neuron Projection Synapse
	Molecular Function	RNA Binding Endoribonuclease Activity Protein Binding 5'-3' Exonuclease Activity Metal Ion Binding	Molecular_function Actin Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Cleavage MRNA 3'-end Processing By Stem-loop Binding And Cleavage MRNA Export From Nucleus MRNA 3'-end Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Regulation Of Cell Growth Cell Cycle Actin Filament Polymerization Positive Regulation Of Cell Migration Positive Regulation Of Protein Ubiquitination Regulation Of Protein Stability Cellular Response To Nutrient Levels Regulation Of Actin Cytoskeleton Organization Cognition Actin Filament Bundle Assembly Negative Regulation Of Focal Adhesion Assembly Regulation Of Microtubule Cytoskeleton Organization Cellular Response To Glucocorticoid Stimulus Negative Regulation Of Long-term Synaptic Potentiation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		Transport of Mature mRNA Derived from an Intronless Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Night sleep phenotypes ( 27126917)
Interacting Genes		6 interacting genes: CLP1 FAM107A HSPB1 PAPOLA POLR2A YWHAG	50 interacting genes: AGMAT APPBP2 AUH AZI2 BEGAIN BIRC8 CALCOCO2 CANX CCDC136 CCDC85B CPSF3 DAPK1 EFEMP2 EFHC2 EIF4A1 FKBP6 FSD2 GFM2 HFM1 HOOK2 HSPA14 HSPD1 HTRA1 IQUB ITPRID2 KRT15 KRT19 KRT40 KRTAP4-12 LDOC1 LZTS2 MEIOB MID2 MTREX NEXN NINL PLSCR1 PNMA1 POMP PSMD6 RAB18 RINT1 RNLS SPATA22 TADA2A TRAF2 TRIM37 USHBP1 VIM WDR47
Entrez ID		51692	11170
HPRD ID		05825	09753
Ensembl ID		ENSG00000119203	ENSG00000168309
Uniprot IDs		G5E9W3 Q9UKF6	A0A024R327 O95990 Q6IAM1
PDB IDs		2I7T 2I7V 6M8Q
Enriched GO Terms of Interacting Partners?
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