GET4 and SEC61B

Number of citations of the paper that reports this interaction (PubMedID 20676083)
113

Data Source:
BioGRID (pull down)

		GET4	SEC61B
Description		guided entry of tail-anchored proteins factor 4	SEC61 translocon subunit beta
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Cytosol BAT3 Complex	Endoplasmic Reticulum Sec61 Translocon Complex Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Membrane Endoplasmic Reticulum Sec Complex
	Molecular Function	Protein Binding Chaperone Binding	RNA Binding ARF Guanyl-nucleotide Exchange Factor Activity Protein Binding Epidermal Growth Factor Binding
	Biological Process	Protein Insertion Into ER Membrane Cytoplasmic Sequestering Of Protein Tail-anchored Membrane Protein Insertion Into ER Membrane Maintenance Of Unfolded Protein Involved In ERAD Pathway	SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Ubiquitin-dependent ERAD Pathway Retrograde Protein Transport, ER To Cytosol Posttranslational Protein Targeting To Membrane, Translocation
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	ER-Phagosome pathway SRP-dependent cotranslational protein targeting to membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS			Callous-unemotional behaviour ( 23874384) Gestational age at birth (maternal effect) ( 28877031) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		21 interacting genes: AKT1 ATP5PD BAG6 CAPNS1 CDKN1A CEP126 EEF1G FLYWCH2 GET3 KAT5 KIFC2 PLK1 PRKAB2 PRKCSH PTMS SEC61B SNCAIP SOD2 TMEM256 TTR UBAC2	11 interacting genes: APOB ARL6 ATP13A2 BAG6 GET3 GET4 SEC63 SERP1 SPC25 TRAM1 UBL4A
Entrez ID		51608	10952
HPRD ID		12909	06715
Ensembl ID		ENSG00000239857	ENSG00000106803
Uniprot IDs		Q7L5D6	P60468
PDB IDs		6AU8
Enriched GO Terms of Interacting Partners?
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