LARP7 and JMJD6

Number of citations of the paper that reports this interaction (PubMedID 23455924)
38

Data Source:
BioGRID (two hybrid)

		LARP7	JMJD6
Description		La ribonucleoprotein 7, transcriptional regulator	jumonji domain containing 6, arginine demethylase and lysine hydroxylase
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Ribonucleoprotein Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding	Transcription Coactivator Activity RNA Binding Single-stranded RNA Binding Iron Ion Binding Protein Binding Demethylase Activity Histone Demethylase Activity Histone Demethylase Activity (H3-R2 Specific) Histone Demethylase Activity (H4-R3 Specific) Oxidative RNA Demethylase Activity Signaling Receptor Activity Identical Protein Binding Peptidyl-lysine 5-dioxygenase Activity P-TEFb Complex Binding
	Biological Process	RNA Processing	Kidney Development Sprouting Angiogenesis MRNA Processing Protein Demethylation Cell Surface Receptor Signaling Pathway Heart Development RNA Splicing Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Lung Development T Cell Differentiation In Thymus Oxidative RNA Demethylation Macrophage Activation Recognition Of Apoptotic Cell Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of MRNA Splicing, Via Spliceosome Erythrocyte Development Protein Homooligomerization Retina Development In Camera-type Eye Histone H3-R2 Demethylation Histone H4-R3 Demethylation
Pathways			HDMs demethylate histones
Drugs
Diseases
GWAS		Body mass index ( 26426971) Dental caries (decayed and filled deciduous teeth) ( 31533690)	Retinal arteriolar caliber ( 23776548)
Interacting Genes		16 interacting genes: APP CHRNB4 GABRG2 GAR1 JMJD6 LRRK2 MCUB OSTC PAPSS1 PPA2 PRPF40A PUF60 RN7SK RRH SMS ZGRF1	27 interacting genes: AEBP2 ANKEF1 BAG5 C17orf97 CCNL1 CENPL DIP2A FGD5 FRMD6 GNA14 H2BC11 H3C1 H4C1 HMGXB4 LARP7 NAA50 NFIX NHP2 PRPF38A PSMC1 RSPO2 SLFN12 SLU7 STAC3 TAF1A U2AF1 ZNF451
Entrez ID		51574	23210
HPRD ID		17095	05371
Ensembl ID		ENSG00000174720	ENSG00000070495
Uniprot IDs		Q4G0J3	Q6NYC1
PDB IDs		4WKR 5KNW 6D12	3K2O 3LD8 3LDB 6BNH 6GDY 6MEV
Enriched GO Terms of Interacting Partners?
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