SIRT6 and CCNDBP1

Number of citations of the paper that reports this interaction (PubMedID 17131381)
19

Data Source:
BioGRID (affinity chromatography technology, pull down)

		SIRT6	CCNDBP1
Description		sirtuin 6	cyclin D1 binding protein 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Telomeric Heterochromatin Nucleolus Cytoplasm	Nucleus Nucleoplasm Cytoplasm Nuclear Body
	Molecular Function	Chromatin Binding Transcription Corepressor Activity NAD+ ADP-ribosyltransferase Activity NAD(P)+-protein-arginine ADP-ribosyltransferase Activity Histone Deacetylase Activity Protein Binding Zinc Ion Binding NAD-dependent Histone Deacetylase Activity Deacetylase Activity NAD-dependent Protein Deacetylase Activity NAD-dependent Histone Deacetylase Activity (H3-K9 Specific) NAD+ Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Post-embryonic Cardiac Muscle Cell Growth Involved In Heart Morphogenesis Base-excision Repair Protein ADP-ribosylation Protein Deacetylation Negative Regulation Of Cell Proliferation Regulation Of Double-strand Break Repair Via Homologous Recombination Protein Destabilization Response To Nutrient Levels Positive Regulation Of Chromatin Silencing At Telomere Positive Regulation Of Telomere Maintenance Glucose Homeostasis Negative Regulation Of Glycolytic Process Negative Regulation Of Glucose Import Positive Regulation Of Fibroblast Proliferation Histone H3-K9 Modification Histone H3 Deacetylation Positive Regulation Of Cold-induced Thermogenesis Positive Regulation Of Transcription Factor Catabolic Process Positive Regulation Of Chondrocyte Proliferation Positive Regulation Of Telomeric Heterochromatin Assembly Positive Regulation Blood Vessel Branching Positive Regulation Of Vascular Endothelial Cell Proliferation Histone H3-K9 Deacetylation Positive Regulation Of Stem Cell Proliferation	Cell Cycle Regulation Of Cell Cycle
Pathways		Pre-NOTCH Transcription and Translation Processing of DNA double-strand break ends
Drugs
Diseases
GWAS
Interacting Genes		17 interacting genes: AKT1 CCNDBP1 CDKN1B CHD3 ELF5 FAF1 HUS1 MUTYH RAD1 SKP2 STUB1 TDG TSPYL2 UBE2D1 UBE3A USP10 VIM	81 interacting genes: AMPD2 ARHGAP22 ATP4B C22orf23 C6orf226 CCDC146 CCND1 CDK18 CDKN2A CFAP65 CNNM3 CUL5 DMRT3 DOCK2 FAM110A FAM126A FAM161A FAM74A4 FH GLIDR GRAP2 GSTK1 HSPB1 ILF2 IMP3 MAP2K2 MOS MRPL15 MRPS9 MTDH NAIF1 NANOS2 NEURL3 NUDCD3 PAXIP1 PIAS2 PIMREG PMP2 PRPF31 PSMB10 PTF1A RBP5 RPL28 RPL39L RPLP0 RPS28 SASH1 SIRT6 SPG7 STK25 SYF2 TEAD4 TFPT THAP10 THAP7 TMEM120B TRAPPC5 TTC23 TYMSOS ZBTB24 ZGPAT ZNF124 ZNF136 ZNF169 ZNF20 ZNF230 ZNF334 ZNF394 ZNF417 ZNF439 ZNF440 ZNF490 ZNF555 ZNF564 ZNF581 ZNF627 ZNF670 ZNF697 ZNF707 ZNRF2P1 ZSCAN26
Entrez ID		51548	23582
HPRD ID		12093	06156
Ensembl ID		ENSG00000077463	ENSG00000166946
Uniprot IDs		B4DDV3 M0QXA0 M0R1N9 Q8N6T7	O95273
PDB IDs		3K35 3PKI 3PKJ 3ZG6 5MF6 5MFP 5MFZ 5MGN 5X16 5Y2F 6HOY	3AY5
Enriched GO Terms of Interacting Partners?
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