CHMP5 and CHMP4B

Number of citations of the paper that reports this interaction (PubMedID 16730941)
60

Data Source:
HPRD (two hybrid)

		CHMP5	CHMP4B
Description		charged multivesicular body protein 5	charged multivesicular body protein 4B
Image
GO Annotations	Cellular Component	Cell Nucleus Cytosol Endosome Membrane Extracellular Exosome	ESCRT III Complex Cell Nucleus Nuclear Envelope Cytoplasm Endosome Cytosol Cytoplasmic Side Of Plasma Membrane Membrane Coat Midbody Late Endosome Membrane Vesicle Extracellular Exosome
	Molecular Function	Protein Binding Cadherin Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding
	Biological Process	Regulation Of Receptor Recycling Nucleus Organization Lysosome Organization Mitotic Metaphase Plate Congression Endosome To Lysosome Transport Regulation Of Centrosome Duplication Protein Transport Endosomal Transport Viral Life Cycle Multivesicular Body Assembly Viral Budding Midbody Abscission Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly ESCRT III Complex Disassembly	Mitotic Cytokinesis Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Autophagy Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Exit From Mitosis Regulation Of Centrosome Duplication Endosomal Transport Macroautophagy Viral Life Cycle Nuclear Envelope Reassembly Multivesicular Body Assembly Maintenance Of Lens Transparency Viral Budding Via Host ESCRT Complex Viral Budding Regulation Of Viral Process Protein Polymerization Negative Regulation Of Cell Death Midbody Abscission Membrane Fission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Neuron Death Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Negative Regulation Of Autophagosome Assembly
Pathways		Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT)	Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III
Drugs
Diseases
GWAS		Erectile dysfunction and prostate cancer treatment ( 20932654)	Feeling nervous ( 29500382) Loneliness ( 27629369) Offspring birth weight ( 31043758) Stearic acid (18:0) levels ( 23362303)
Interacting Genes		17 interacting genes: APPBP2 CHMP1B CHMP4A CHMP4B GTF3A MITD1 NOD2 NUP98 PDCD10 RPL38 SMARCA4 STAMBP URGCP VPS4B VTA1 ZNF142 ZNF91	15 interacting genes: CHMP1B CHMP3 CHMP4A CHMP4C CHMP5 CHMP6 EXOSC9 HIPK2 NOD2 PDCD6IP PIAS2 PTPN23 STAMBP UBE2I VPS4A
Entrez ID		51510	128866
HPRD ID		15408	16642
Ensembl ID		ENSG00000086065	ENSG00000101421
Uniprot IDs		Q9NZZ3	Q9H444
PDB IDs		2LXM 3ULY 3UM0 3UM1 3UM2 4TXR	3C3Q 3UM3 4ABM 5MK2
Enriched GO Terms of Interacting Partners?
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