CHMP4B and CHMP3

Number of citations of the paper that reports this interaction (PubMedID 14505570)
373

Data Source:
HPRD (two hybrid)

		CHMP4B	CHMP3
Description		charged multivesicular body protein 4B	charged multivesicular body protein 3
Image
GO Annotations	Cellular Component	ESCRT III Complex Cell Nucleus Nuclear Envelope Cytoplasm Endosome Cytosol Cytoplasmic Side Of Plasma Membrane Membrane Coat Midbody Late Endosome Membrane Vesicle Extracellular Exosome	ESCRT III Complex Cell Late Endosome Multivesicular Body Cytosol Plasma Membrane Cytoplasmic Vesicle Late Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding	Protein Binding Phosphatidylcholine Binding Ubiquitin-specific Protease Binding
	Biological Process	Mitotic Cytokinesis Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Autophagy Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Exit From Mitosis Regulation Of Centrosome Duplication Endosomal Transport Macroautophagy Viral Life Cycle Nuclear Envelope Reassembly Multivesicular Body Assembly Maintenance Of Lens Transparency Viral Budding Via Host ESCRT Complex Viral Budding Regulation Of Viral Process Protein Polymerization Negative Regulation Of Cell Death Midbody Abscission Membrane Fission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Neuron Death Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Negative Regulation Of Autophagosome Assembly	Apoptotic Process Nucleus Organization Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Late Endosome To Vacuole Transport Regulation Of Viral Process Protein Polymerization Multivesicular Body-lysosome Fusion Midbody Abscission Multivesicular Body Sorting Pathway Autophagosome Maturation Regulation Of Mitotic Spindle Assembly Negative Regulation Of Viral Release From Host Cell Positive Regulation Of Viral Release From Host Cell Regulation Of Exosomal Secretion Regulation Of Early Endosome To Late Endosome Transport
Pathways		Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III	Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III
Drugs
Diseases
GWAS		Feeling nervous ( 29500382) Loneliness ( 27629369) Offspring birth weight ( 31043758) Stearic acid (18:0) levels ( 23362303)	Glomerular filtration rate in chronic kidney disease ( 26420894)
Interacting Genes		15 interacting genes: CHMP1B CHMP3 CHMP4A CHMP4C CHMP5 CHMP6 EXOSC9 HIPK2 NOD2 PDCD6IP PIAS2 PTPN23 STAMBP UBE2I VPS4A	13 interacting genes: APP CHMP2A CHMP2B CHMP4A CHMP4B FBXO7 IGFBP7 RAB11A SMAD1 SMAD5 STAMBP TNPO3 VAV2
Entrez ID		128866	51652
HPRD ID		16642	15650
Ensembl ID		ENSG00000101421	ENSG00000115561
Uniprot IDs		Q9H444	Q9Y3E7
PDB IDs		3C3Q 3UM3 4ABM 5MK2	2GD5 2XZE 3FRT 3FRV
Enriched GO Terms of Interacting Partners?
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