EVL and APBB1IP

Number of citations of the paper that reports this interaction (PubMedID 15469846)
153

Data Source:
HPRD (in vivo)

		EVL	APBB1IP
Description		Enah/Vasp-like	amyloid beta precursor protein binding family B member 1 interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Focal Adhesion Membrane Lamellipodium Phagocytic Vesicle	Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Lamellipodium T Cell Receptor Complex
	Molecular Function	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding	Protein Binding
	Biological Process	Actin Filament Organization Cell Surface Receptor Signaling Pathway Nervous System Development Axon Guidance Actin Polymerization Or Depolymerization Animal Organ Morphogenesis Negative Regulation Of Epithelial Cell Migration Positive Regulation Of Actin Filament Polymerization Actin Nucleation Protein Homotetramerization Positive Regulation Of Stress Fiber Assembly Cellular Response To Interferon-gamma Negative Regulation Of Ruffle Assembly	T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Signal Transduction Positive Regulation Of Cell Adhesion
Pathways		Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors RHO GTPases Activate Formins	Integrin signaling GRB2:SOS provides linkage to MAPK signaling for Integrins p130Cas linkage to MAPK signaling for integrins MAP2K and MAPK activation Signaling by moderate kinase activity BRAF mutants Signaling by high-kinase activity BRAF mutants Signaling by BRAF and RAF fusions Paradoxical activation of RAF signaling by kinase inactive BRAF Signaling downstream of RAS mutants
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) White matter hyperintensity burden ( 25663218)	Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Inflammatory biomarkers ( 22228203) Monocyte percentage of white cells ( 27863252) Neutrophil percentage of granulocytes ( 27863252) Response to angiotensin II receptor blocker therapy ( 22566498) Sum eosinophil basophil counts ( 27863252) White blood cell count (basophil) ( 27863252)
Interacting Genes		30 interacting genes: ABI1 ABI3 ABL1 APBB1 APBB1IP CRKL DNMBP ENAH FYB1 FYN HCK HTT LYN PFN2 POT1 PRPF40A RAD51 SEMA6A SPTA1 SPTAN1 SRC TCERG1 TERF1 TES TRIM9 VASP WAS WASL XIRP1 ZDHHC17	10 interacting genes: EVL GAS7 HRAS NDN PFN1 PRPF40A RAB18 RAP1A VASP ZDHHC17
Entrez ID		51466	54518
HPRD ID		10942	16420
Ensembl ID		ENSG00000196405	ENSG00000077420
Uniprot IDs		A0A024R6K5 Q9UI08	Q7Z5R6
PDB IDs			2MWN 3ZDL
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?