AMOTL2 and NFIL3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		AMOTL2	NFIL3
Description		angiomotin like 2	nuclear factor, interleukin 3 regulated
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Bicellular Tight Junction Apical Plasma Membrane Cytoplasmic Vesicle Recycling Endosome	Nuclear Chromatin Nucleus
	Molecular Function	Protein Binding Identical Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding
	Biological Process	Angiogenesis Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Wnt Signaling Pathway Actin Cytoskeleton Organization Regulation Of Cell Migration Hippo Signaling	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Immune Response Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Cellular Response To Interleukin-4
Pathways		Signaling by Hippo	Circadian Clock
Drugs
Diseases
GWAS		Cadmium levels ( 26025379) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)	Bipolar disorder (inflammation and infection response interaction) ( 25781172) Birth weight ( 31043758) Inflammatory bowel disease ( 23128233) Offspring birth weight ( 31043758)
Interacting Genes		57 interacting genes: BLZF1 BRMS1L CARD9 CCHCR1 CDR2 CHCHD3 CYTH4 DDIT3 DYNLL1 EIF4E2 FAM184A FBXO7 FXR2 GCC1 GNG11 GNG5 GOLGA2 GSTM5 KRT13 KRT15 KRT19 KRT20 KRT31 KRT38 KRTAP10-5 KRTAP4-2 LMO4 MAD1L1 MAGEA4 MAGOHB MFAP1 MPP1 MTMR6 MTNR1A MYO5B NDC80 NFIL3 NTAQ1 PSMC3 RAD51D RALBP1 RASSF5 RNF20 RNF40 SH3RF2 SMARCE1 SP100 SPAG5 SPOP SPP1 THRA TMCC2 TNKS2 TRAF2 TRIM27 ZBED1 ZGPAT	10 interacting genes: AMOTL2 BATF CREB3 DDIT3 DELEC1 DNMT3L DR1 MAFF MAFG TRAF2
Entrez ID		51421	4783
HPRD ID		16485	05619
Ensembl ID		ENSG00000114019	ENSG00000165030
Uniprot IDs		Q9Y2J4	A0A024R241 Q16649
PDB IDs
Enriched GO Terms of Interacting Partners?
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