AMOTL2 and RASSF5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		AMOTL2	RASSF5
Description		angiomotin like 2	Ras association domain family member 5
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Bicellular Tight Junction Apical Plasma Membrane Cytoplasmic Vesicle Recycling Endosome	Nucleus Cytoplasm Microtubule
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Ras GTPase Binding Metal Ion Binding
	Biological Process	Angiogenesis Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Wnt Signaling Pathway Actin Cytoskeleton Organization Regulation Of Cell Migration Hippo Signaling	Apoptotic Process Negative Regulation Of Cell Proliferation Positive Regulation Of Protein Ubiquitination Intracellular Signal Transduction Regulation Of Apoptotic Process Regulation Of Protein Localization To Nucleus
Pathways		Signaling by Hippo
Drugs
Diseases
GWAS		Cadmium levels ( 26025379) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)	Inflammatory bowel disease ( 23128233) Late-onset Alzheimer's disease ( 27770636) Neurofibrillary tangles ( 25188341)
Interacting Genes		57 interacting genes: BLZF1 BRMS1L CARD9 CCHCR1 CDR2 CHCHD3 CYTH4 DDIT3 DYNLL1 EIF4E2 FAM184A FBXO7 FXR2 GCC1 GNG11 GNG5 GOLGA2 GSTM5 KRT13 KRT15 KRT19 KRT20 KRT31 KRT38 KRTAP10-5 KRTAP4-2 LMO4 MAD1L1 MAGEA4 MAGOHB MFAP1 MPP1 MTMR6 MTNR1A MYO5B NDC80 NFIL3 NTAQ1 PSMC3 RAD51D RALBP1 RASSF5 RNF20 RNF40 SH3RF2 SMARCE1 SP100 SPAG5 SPOP SPP1 THRA TMCC2 TNKS2 TRAF2 TRIM27 ZBED1 ZGPAT	30 interacting genes: ADH6 AMOTL2 APPBP2 BTRC HRAS ITCH KRAS KRT40 KRTAP4-2 LSM7 MRAS MYLIP NRAS RABIF RALA RAP1B RAP2A RAP2B RASSF1 RASSF2 REL RRAS RRAS2 SMAD4 STK4 TERF2IP TRAF1 TRAF2 UBQLN1 VPS28
Entrez ID		51421	83593
HPRD ID		16485	06117
Ensembl ID		ENSG00000114019	ENSG00000266094
Uniprot IDs		Q9Y2J4	A8K5F3 Q8WWW0
PDB IDs			4LGD 4OH8
Enriched GO Terms of Interacting Partners?
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