SNX7 and HMOX2

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		SNX7	HMOX2
Description		sorting nexin 7	heme oxygenase 2
Image
GO Annotations	Cellular Component	Cytoplasmic Vesicle Membrane	Cell Endoplasmic Reticulum Membrane Plasma Membrane Membrane Specific Granule Membrane
	Molecular Function	Protein Binding Phosphatidylinositol Binding	Heme Oxygenase (decyclizing) Activity Protein Binding Heme Binding Metal Ion Binding
	Biological Process	Protein Transport	Response To Hypoxia Heme Oxidation Cellular Iron Ion Homeostasis Response To Oxidative Stress Heme Catabolic Process Neutrophil Degranulation Iron Ion Homeostasis
Pathways			Heme degradation Neutrophil degranulation Iron uptake and transport
Drugs			NADH Stannsoporfin
Diseases
GWAS		Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Copper levels ( 26025379) Dental caries ( 23259602) Disease progression in age-related macular degeneration ( 29346644) General risk tolerance (MTAG) ( 30643258) LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Methadone dose in opioid dependence ( 28115739) Night sleep phenotypes ( 27126917) Proinsulin levels ( 21873549) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097 31123309)	Erectile dysfunction ( 30583798)
Interacting Genes		7 interacting genes: BIRC3 HGS HMOX2 MAGEA11 MESD POLR2L TEX11	35 interacting genes: A2M APP ATP5F1B BLOC1S2 CEBPZ CEP126 COPS6 CSNK2A1 EEF1G EIF3C GIT1 GPRASP1 HAP1 IMMT INPP5K ITFG1 JADE1 KCNMA1 LMNA LRIF1 MARK3 MED31 MTNR1A NDUFS2 NKRF NR3C1 PLXNB2 RBBP4 SETDB1 SHC1 SKA2 SNX5 SNX7 ZFP28 ZNF746
Entrez ID		51375	3163
HPRD ID		15416	00783
Ensembl ID		ENSG00000162627	ENSG00000103415
Uniprot IDs		B4DP69 E9PNL2 Q9UNH6	A0A087WT44 B3KSE0 P30519
PDB IDs		3IQ2	2Q32 2QPP 2RGZ 4WMH 5UC8 5UC9 5UCA
Enriched GO Terms of Interacting Partners?
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