HMOX2 and SNX7

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		HMOX2	SNX7
Description		heme oxygenase 2	sorting nexin 7
Image
GO Annotations	Cellular Component	Cell Endoplasmic Reticulum Membrane Plasma Membrane Membrane Specific Granule Membrane	Cytoplasmic Vesicle Membrane
	Molecular Function	Heme Oxygenase (decyclizing) Activity Protein Binding Heme Binding Metal Ion Binding	Protein Binding Phosphatidylinositol Binding
	Biological Process	Response To Hypoxia Heme Oxidation Cellular Iron Ion Homeostasis Response To Oxidative Stress Heme Catabolic Process Neutrophil Degranulation Iron Ion Homeostasis	Protein Transport
Pathways		Heme degradation Neutrophil degranulation Iron uptake and transport
Drugs		NADH Stannsoporfin
Diseases
GWAS		Erectile dysfunction ( 30583798)	Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Copper levels ( 26025379) Dental caries ( 23259602) Disease progression in age-related macular degeneration ( 29346644) General risk tolerance (MTAG) ( 30643258) LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Methadone dose in opioid dependence ( 28115739) Night sleep phenotypes ( 27126917) Proinsulin levels ( 21873549) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097 31123309)
Interacting Genes		35 interacting genes: A2M APP ATP5F1B BLOC1S2 CEBPZ CEP126 COPS6 CSNK2A1 EEF1G EIF3C GIT1 GPRASP1 HAP1 IMMT INPP5K ITFG1 JADE1 KCNMA1 LMNA LRIF1 MARK3 MED31 MTNR1A NDUFS2 NKRF NR3C1 PLXNB2 RBBP4 SETDB1 SHC1 SKA2 SNX5 SNX7 ZFP28 ZNF746	7 interacting genes: BIRC3 HGS HMOX2 MAGEA11 MESD POLR2L TEX11
Entrez ID		3163	51375
HPRD ID		00783	15416
Ensembl ID		ENSG00000103415	ENSG00000162627
Uniprot IDs		A0A087WT44 B3KSE0 P30519	B4DP69 E9PNL2 Q9UNH6
PDB IDs		2Q32 2QPP 2RGZ 4WMH 5UC8 5UC9 5UCA	3IQ2
Enriched GO Terms of Interacting Partners?
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