KLF3 and LHX8

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KLF3	LHX8
Description		Kruppel like factor 3	LIM homeobox 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm	Nuclear Chromatin Female Germ Cell Nucleus Nucleus
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Cellular Response To Peptide	Learning Or Memory Female Gonad Development Forebrain Neuron Development Neuron Differentiation Odontogenesis Of Dentin-containing Tooth Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Crohn's disease ( 23850713) Endometriosis or endometrial cancer (pleiotropy) ( 29608257) Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Hand grip strength ( 29691431) Helicobacter pylori serologic status ( 23652523) Lymphocyte counts ( 27863252) Multiple sclerosis ( 31604244) Neutrophil percentage of granulocytes ( 27863252) Sum eosinophil basophil counts ( 27863252) White blood cell count ( 27863252)
Interacting Genes		12 interacting genes: CTBP1 CTBP2 DVL3 EHMT2 FHL3 KDM1A LHX8 LSM3 PIAS1 SUV39H2 TRAF2 UBE2I	8 interacting genes: AXIN1 CRK KLF3 LDB1 NUTM1 PLCG2 SCYL3 SUV39H1
Entrez ID		51274	431707
HPRD ID		13920	17275
Ensembl ID		ENSG00000109787	ENSG00000162624
Uniprot IDs		P57682	Q68G74
PDB IDs
Enriched GO Terms of Interacting Partners?
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