LHX8 and KLF3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		LHX8	KLF3
Description		LIM homeobox 8	Kruppel like factor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Female Germ Cell Nucleus Nucleus	Nuclear Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	Learning Or Memory Female Gonad Development Forebrain Neuron Development Neuron Differentiation Odontogenesis Of Dentin-containing Tooth Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Cellular Response To Peptide
Pathways
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29785011) Crohn's disease ( 23850713) Endometriosis or endometrial cancer (pleiotropy) ( 29608257) Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Hand grip strength ( 29691431) Helicobacter pylori serologic status ( 23652523) Lymphocyte counts ( 27863252) Multiple sclerosis ( 31604244) Neutrophil percentage of granulocytes ( 27863252) Sum eosinophil basophil counts ( 27863252) White blood cell count ( 27863252)
Interacting Genes		8 interacting genes: AXIN1 CRK KLF3 LDB1 NUTM1 PLCG2 SCYL3 SUV39H1	12 interacting genes: CTBP1 CTBP2 DVL3 EHMT2 FHL3 KDM1A LHX8 LSM3 PIAS1 SUV39H2 TRAF2 UBE2I
Entrez ID		431707	51274
HPRD ID		17275	13920
Ensembl ID		ENSG00000162624	ENSG00000109787
Uniprot IDs		Q68G74	P57682
PDB IDs
Enriched GO Terms of Interacting Partners?
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