TBC1D7 and BAG4

Number of citations of the paper that reports this interaction (PubMedID 27107012)
28

Data Source:
BioGRID (two hybrid)

		TBC1D7	BAG4
Description		TBC1 domain family member 7	BAG cochaperone 4
Image
GO Annotations	Cellular Component	Cytosol Cytoplasmic Vesicle Ciliary Basal Body	Nucleus Cytosol Plasma Membrane
	Molecular Function	GTPase Activator Activity Protein Binding Rab GTPase Binding	RNA Binding Protein Binding Ubiquitin Protein Ligase Binding Chaperone Binding
	Biological Process	Positive Regulation Of Protein Ubiquitination Negative Regulation Of TOR Signaling Positive Regulation Of GTPase Activity Response To Growth Factor Activation Of GTPase Activity Negative Regulation Of Cilium Assembly	Protein Folding Positive Regulation Of Fibroblast Migration Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Peptidyl-serine Phosphorylation Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Apoptotic Process Positive Regulation Of Cell Adhesion Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Protein Kinase B Signaling Cellular Response To Tumor Necrosis Factor Cellular Response To Epidermal Growth Factor Stimulus Protein Localization To Plasma Membrane Ruffle Assembly Regulation Of Cellular Response To Heat Negative Regulation Of Protein Targeting To Mitochondrion Negative Regulation Of Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity
Pathways		TBC/RABGAPs	Regulation of HSF1-mediated heat shock response Signaling by FGFR1 in disease TNF signaling Signaling by plasma membrane FGFR1 fusions
Drugs
Diseases
GWAS		Migraine ( 23793025) Migraine without aura ( 23793025)	Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 28991256 29483656)
Interacting Genes		19 interacting genes: AKT1 APP BAG4 BLZF1 GABARAPL1 HOOK1 IKBKG KRT19 LDOC1 LNX2 LZTS2 MAP1LC3A NEDD4 NEDD4L RPGRIP1 SSNA1 TRAF4 TSC1 YWHAZ	38 interacting genes: APOBEC1 ATAD2 BAP1 BCAS3 BCL2 BEX1 CASZ1 CCL5 DIRAS3 EPSTI1 ERRFI1 GLCE GRAP2 HSPA1A HSPA8 IL13RA2 IL24 ITIH5 KLK5 KLK7 KLK9 LRATD2 LYPD3 MRC2 MTA3 NAT2 PDLIM2 PLAT PRDM14 RASL10B RHOBTB2 RNF20 RPL22 SCGB3A1 TBC1D7 THRSP TNFRSF1A TNFRSF25
Entrez ID		51256	9530
HPRD ID		18165	04861
Ensembl ID		ENSG00000145979	ENSG00000156735
Uniprot IDs		A0A024QZX0 A0A024R011 Q5JPB9 Q9P0N9 U3KPY5	O95429
PDB IDs		3QWL 4Z6Y 5EJC 5ULO	1M62 1M7K
Enriched GO Terms of Interacting Partners?
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