PCNT and SH3BGR

		PCNT	SH3BGR
Description		pericentrin	SH3 domain binding glutamate rich protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Centrosome Centriole Cytosol Microtubule Membrane Centriolar Satellite	Cytosol
	Molecular Function	Protein Binding Calmodulin Binding Molecular Adaptor Activity	SH3/SH2 Adaptor Activity SH3 Domain Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Mitotic Spindle Organization Signal Transduction Regulation Of G2/M Transition Of Mitotic Cell Cycle Cilium Assembly Positive Regulation Of Intracellular Protein Transport Ciliary Basal Body-plasma Membrane Docking	Positive Regulation Of Signal Transduction Protein-containing Complex Assembly
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2 Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy Aggrephagy
Drugs
Diseases		Microcephalic osteodysplastic primordial dwarfism, type II (MOPD II) Seckel syndrome
GWAS		Heel bone mineral density ( 30598549) Pre-treatment viral load in HIV-1 infection ( 31219150) Treatment resistant depression ( 30468137)
Interacting Genes		21 interacting genes: AKAP9 CALM1 CALM2 CCP110 CDK12 CEP55 COL6A1 DISC1 HPRT1 NDUFV3 PCM1 PDE9A PFKL PKNOX1 RAC3 S100B SH3BGR TP53BP1 TUBG1 TUBGCP2 TUBGCP3	3 interacting genes: CAPN1 FCHSD2 PCNT
Entrez ID		5116	6450
HPRD ID		05804	03753
Ensembl ID		ENSG00000160299	ENSG00000185437
Uniprot IDs		O95613	C9JJT2 P55822
PDB IDs
Enriched GO Terms of Interacting Partners?
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