AMDHD2 and GNPDA2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, biochemical)

		AMDHD2	GNPDA2
Description		amidohydrolase domain containing 2	glucosamine-6-phosphate deaminase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding N-acetylglucosamine-6-phosphate Deacetylase Activity Metal Ion Binding N-acetylgalactosamine-6-phosphate Deacetylase Activity	Glucosamine-6-phosphate Deaminase Activity Protein Binding Identical Protein Binding
	Biological Process	Carbohydrate Metabolic Process N-acetylglucosamine Catabolic Process UDP-N-acetylglucosamine Biosynthetic Process N-acetylneuraminate Catabolic Process	Carbohydrate Metabolic Process Glucosamine Catabolic Process N-acetylglucosamine Catabolic Process UDP-N-acetylglucosamine Biosynthetic Process N-acetylneuraminate Catabolic Process
Pathways		Synthesis of UDP-N-acetyl-glucosamine	Glycolysis
Drugs
Diseases
GWAS			BMI (adjusted for smoking behaviour) ( 28443625) BMI at adiposity rebound ( 31840077) BMI in non-smokers ( 28443625) BMI in smokers ( 28443625) Body mass index ( 23563607 19079261 26961502 23669352 24861553 31453325 28892062 25673413 20935630 23583978 28448500) Body mass index (adult) ( 28430825) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Body mass index in physically inactive individuals ( 28448500) Body mass index variance ( 31453325) Childhood body mass index ( 26604143) General risk tolerance (MTAG) ( 30643258) Hand grip strength ( 29691431) Hip circumference ( 25673412) Menarche (age at onset) ( 25231870) Metabolite levels ( 23823483) Obese vs. thin ( 30677029) Obesity ( 23563607) Obesity (extreme) ( 30677029) Systolic blood pressure ( 26969751) Type 2 diabetes ( 30297969 30718926) Waist circumference ( 31453325 25673412) Waist circumference variance ( 31453325)
Interacting Genes		2 interacting genes: GNPDA2 TRIP13	3 interacting genes: AMDHD2 ERRFI1 TRIM27
Entrez ID		51005	132789
HPRD ID		13034	13594
Ensembl ID		ENSG00000162066	ENSG00000163281
Uniprot IDs		A0A3B3IU33 Q9Y303	A0A024R9X5 Q8TDQ7
PDB IDs
Enriched GO Terms of Interacting Partners?
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