GNPDA2 and AMDHD2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, biochemical)

		GNPDA2	AMDHD2
Description		glucosamine-6-phosphate deaminase 2	amidohydrolase domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleus Cytosol
	Molecular Function	Glucosamine-6-phosphate Deaminase Activity Protein Binding Identical Protein Binding	Protein Binding N-acetylglucosamine-6-phosphate Deacetylase Activity Metal Ion Binding N-acetylgalactosamine-6-phosphate Deacetylase Activity
	Biological Process	Carbohydrate Metabolic Process Glucosamine Catabolic Process N-acetylglucosamine Catabolic Process UDP-N-acetylglucosamine Biosynthetic Process N-acetylneuraminate Catabolic Process	Carbohydrate Metabolic Process N-acetylglucosamine Catabolic Process UDP-N-acetylglucosamine Biosynthetic Process N-acetylneuraminate Catabolic Process
Pathways		Glycolysis	Synthesis of UDP-N-acetyl-glucosamine
Drugs
Diseases
GWAS		BMI (adjusted for smoking behaviour) ( 28443625) BMI at adiposity rebound ( 31840077) BMI in non-smokers ( 28443625) BMI in smokers ( 28443625) Body mass index ( 23563607 19079261 26961502 23669352 24861553 31453325 28892062 25673413 20935630 23583978 28448500) Body mass index (adult) ( 28430825) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Body mass index in physically inactive individuals ( 28448500) Body mass index variance ( 31453325) Childhood body mass index ( 26604143) General risk tolerance (MTAG) ( 30643258) Hand grip strength ( 29691431) Hip circumference ( 25673412) Menarche (age at onset) ( 25231870) Metabolite levels ( 23823483) Obese vs. thin ( 30677029) Obesity ( 23563607) Obesity (extreme) ( 30677029) Systolic blood pressure ( 26969751) Type 2 diabetes ( 30297969 30718926) Waist circumference ( 31453325 25673412) Waist circumference variance ( 31453325)
Interacting Genes		3 interacting genes: AMDHD2 ERRFI1 TRIM27	2 interacting genes: GNPDA2 TRIP13
Entrez ID		132789	51005
HPRD ID		13594	13034
Ensembl ID		ENSG00000163281	ENSG00000162066
Uniprot IDs		A0A024R9X5 Q8TDQ7	A0A3B3IU33 Q9Y303
PDB IDs
Enriched GO Terms of Interacting Partners?
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