ATP5F1C and ITIH2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ATP5F1C	ITIH2
Description		ATP synthase F1 subunit gamma	inter-alpha-trypsin inhibitor heavy chain 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrial Proton-transporting ATP Synthase Complex, Catalytic Core F(1) Mitochondrion Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Matrix Membrane	Extracellular Region Endoplasmic Reticulum Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle
	Molecular Function	RNA Binding ATPase Activity Proton-transporting ATP Synthase Activity, Rotational Mechanism	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity
	Biological Process	Oxidative Phosphorylation ATP Biosynthetic Process ATP Synthesis Coupled Proton Transport Cristae Formation Mitochondrial ATP Synthesis Coupled Proton Transport	Negative Regulation Of Endopeptidase Activity Hyaluronan Metabolic Process Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Formation of ATP by chemiosmotic coupling Cristae formation	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs		Quercetin 1-ACETYL-2-CARBOXYPIPERIDINE AUROVERTIN B PICEATANNOL N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE	Zinc Copper
Diseases
GWAS			Blood protein levels ( 30072576 29875488) Ovarian reserve ( 22116950)
Interacting Genes		25 interacting genes: APP ATP5F1A ATP5F1B CA12 CCND3 CCT7 CHMP2B DPP3 EGFR ELOF1 FBXO7 GDPD2 ITIH2 MED15 MPP1 NDUFB3 NGEF PAWR PJA1 PNO1 POLA2 PTEN PTN SERPINA1 ZNF337	3 interacting genes: ATP5F1C FCER1A SPINT2
Entrez ID		509	3698
HPRD ID		00156	00890
Ensembl ID		ENSG00000165629	ENSG00000151655
Uniprot IDs		B4DL14 P36542 Q8TAS0	P19823
PDB IDs
Enriched GO Terms of Interacting Partners?
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