ROR1 and DUPD1

Number of citations of the paper that reports this interaction (PubMedID 28065597)
26

Data Source:
BioGRID (two hybrid)

		ROR1	DUPD1
Description		receptor tyrosine kinase like orphan receptor 1	dual specificity phosphatase and pro isomerase domain containing 1
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GO Annotations	Cellular Component	Stress Fiber Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Axon Receptor Complex Axon Terminus	Cytoplasm Protein-containing Complex
	Molecular Function	Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Binding ATP Binding Wnt-protein Binding Wnt-activated Receptor Activity Coreceptor Activity Involved In Wnt Signaling Pathway, Planar Cell Polarity Pathway	Protein Tyrosine Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity Protein Homodimerization Activity
	Biological Process	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Nervous System Development Sensory Perception Of Sound Positive Regulation Of Neuron Projection Development Astrocyte Development Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Peptidyl-tyrosine Phosphorylation Positive Regulation Of Kinase Activity Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of MAPK Cascade Positive Regulation Of MAPK Cascade Inner Ear Development Anatomical Structure Development Positive Regulation Of NF-kappaB Transcription Factor Activity Wnt Signaling Pathway, Planar Cell Polarity Pathway Positive Regulation Of ERK1 And ERK2 Cascade	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation
Pathways		WNT5A-dependent internalization of FZD2, FZD5 and ROR2
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Normal facial asymmetry (angle of surface orientation score) ( 30631343) Pancreatic cancer ( 26098869) Severe bacterial meningitis ( 31092817)	Anxiety disorder ( 25390645) Height ( 31562340)
Interacting Genes		13 interacting genes: APP DUPD1 DUSP14 DUSP18 DUSP19 DUSP21 ILKAP MFHAS1 PPM1B PPM1F PTPN6 PTPRR STYX	8 interacting genes: AATK EPHA2 ERBB3 IGF1R LMTK2 PTK7 ROR1 ROR2
Entrez ID		4919	338599
HPRD ID		03821	16846
Ensembl ID		ENSG00000185483	ENSG00000188716
Uniprot IDs		Q01973	Q68J44
PDB IDs		5Z55 6BA5 6BAN	2Y96
Enriched GO Terms of Interacting Partners?
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