NME4 and SUV39H2

Number of citations of the paper that reports this interaction (PubMedID 23455924)
38

Data Source:
BioGRID (two hybrid)

		NME4	SUV39H2
Description		NME/NM23 nucleoside diphosphate kinase 4	suppressor of variegation 3-9 homolog 2
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Mitochondrial Matrix	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm
	Molecular Function	Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding Metal Ion Binding Cardiolipin Binding	Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding Zinc Ion Binding Histone Methyltransferase Activity (H3-K9 Specific) S-adenosyl-L-methionine Binding
	Biological Process	Purine Nucleotide Metabolic Process Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process Pyrimidine Nucleotide Metabolic Process UTP Biosynthetic Process CTP Biosynthetic Process Lipid Transport Nucleoside Metabolic Process Nucleobase-containing Small Molecule Interconversion Regulation Of Apoptotic Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Assembly Or Disassembly Chromatin Remodeling Cell Cycle Cell Differentiation Histone Lysine Methylation Histone H3-K9 Dimethylation Histone H3-K9 Trimethylation Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Cellular Response To Hypoxia
Pathways		Interconversion of nucleotide di- and triphosphates	PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Body mass index ( 26426971) Red blood cell traits ( 23446634)	Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		8 interacting genes: CLNK LSM8 NME1 NME1-NME2 SOCS3 SUV39H2 TNS4 TRIP13	40 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CCDC151 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GSTCD ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 WIZ ZNF212 ZNF557 ZNF57
Entrez ID		4833	79723
HPRD ID		03489	07580
Ensembl ID		ENSG00000103202	ENSG00000152455
Uniprot IDs		A0A087WVT9 O00746	Q9H5I1
PDB IDs		1EHW	2R3A 6P0R
Enriched GO Terms of Interacting Partners?
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