SUV39H2 and ZNF557

Number of citations of the paper that reports this interaction (PubMedID 23455924)
38

Data Source:
BioGRID (two hybrid)

		SUV39H2	ZNF557
Description		suppressor of variegation 3-9 homolog 2	zinc finger protein 557
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm	Nucleus
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding Zinc Ion Binding Histone Methyltransferase Activity (H3-K9 Specific) S-adenosyl-L-methionine Binding	DNA-binding Transcription Factor Activity Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Assembly Or Disassembly Chromatin Remodeling Cell Cycle Cell Differentiation Histone Lysine Methylation Histone H3-K9 Dimethylation Histone H3-K9 Trimethylation Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Cellular Response To Hypoxia	Regulation Of Transcription, DNA-templated
Pathways		PKMTs methylate histone lysines	Generic Transcription Pathway
Drugs
Diseases
GWAS		Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		40 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CCDC151 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GSTCD ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 WIZ ZNF212 ZNF557 ZNF57	10 interacting genes: CEP70 CRK MTUS2 NSD3 PRMT6 SMAD9 SMYD3 STAT3 SUV39H1 SUV39H2
Entrez ID		79723	79230
HPRD ID		07580	15840
Ensembl ID		ENSG00000152455	ENSG00000130544
Uniprot IDs		Q9H5I1	Q8N988
PDB IDs		2R3A 6P0R
Enriched GO Terms of Interacting Partners?
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