NFKBIB and LRPPRC

Number of citations of the paper that reports this interaction (PubMedID 14743216)
300

Data Source:
HPRD (in vitro)

		NFKBIB	LRPPRC
Description		NFKB inhibitor beta	leucine rich pentatricopeptide repeat containing
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Condensed Nuclear Chromosome Nucleus Nuclear Inner Membrane Nuclear Outer Membrane Nucleoplasm Mitochondrion Cytoskeleton Microtubule Membrane Mitochondrial Nucleoid Perinuclear Region Of Cytoplasm Ribonucleoprotein Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding	Single-stranded DNA Binding RNA Binding Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding Actin Filament Binding
	Biological Process	Transcription, DNA-templated Signal Transduction Cellular Response To Lipopolysaccharide Positive Regulation Of Nucleic Acid-templated Transcription	Negative Regulation Of Mitochondrial RNA Catabolic Process Mitochondrion Transport Along Microtubule MRNA Transport Regulation Of Mitochondrial Translation
Pathways		Activation of NF-kappaB in B cells RIP-mediated NFkB activation via ZBP1 TAK1 activates NFkB by phosphorylation and activation of IKKs complex TRAF6 mediated NF-kB activation	TP53 Regulates Metabolic Genes Respiratory electron transport
Drugs
Diseases
GWAS			Alcohol consumption (drinks per week) ( 30679032) Bitter alcoholic beverage consumption ( 31046077) Chronotype ( 30696823) Hand grip strength ( 29691431 29313844) Medication use (calcium channel blockers) ( 31015401) Medication use (HMG CoA reductase inhibitors) ( 31015401) Morning person ( 30696823) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		41 interacting genes: APP BAK1 BTRC CD3EAP CDC25A CHUK CSNK2A1 CUL1 DNAJA3 ESR2 FHL3 GIT2 IKBKB IKBKG KPNA2 LRPPRC MCC MTIF2 NCOR2 NFKB1 NFKB2 NFKBIA NGFR NKIRAS1 NKIRAS2 PDCD2 POLR1A POLR1B POLR1C POLR1D POLR1E POLR2H POLR2L PPARG RASAL2 REL RELA RXRA SKP1 TSPAN1 VPS52	8 interacting genes: AP2A2 CECR2 FOXO1 HEBP2 MAP1S NFKBIB PPARGC1A UXT
Entrez ID		4793	10128
HPRD ID		07260	06343
Ensembl ID		ENSG00000104825	ENSG00000138095
Uniprot IDs		G5E9C2 Q15653	E5KNY5 P42704
PDB IDs
Enriched GO Terms of Interacting Partners?
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