NFIC and TEAD2

Number of citations of the paper that reports this interaction (PubMedID 28205554)
32

Data Source:
BioGRID (fluorescent resonance energy transfer)

		NFIC	TEAD2
Description		nuclear factor I C	TEA domain transcription factor 2
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Fibrillar Center Nucleus Nucleoplasm	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Cytosol Intracellular Membrane-bounded Organelle TEAD-2-YAP Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding Transcription Coactivator Binding DNA-binding Transcription Factor Activity Transcription Coregulator Activity Protein Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity Disordered Domain Specific Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Replication Transcription By RNA Polymerase II Odontogenesis Of Dentin-containing Tooth Positive Regulation Of Transcription By RNA Polymerase II	Vasculogenesis Neural Tube Closure Embryonic Heart Tube Morphogenesis Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Notochord Development Hippo Signaling Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Paraxial Mesoderm Development Lateral Mesoderm Development Embryonic Organ Development Negative Regulation Of Cell Death Protein-containing Complex Assembly Cellular Response To Retinoic Acid Regulation Of Stem Cell Differentiation
Pathways		RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation	YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX3 regulates YAP1-mediated transcription
Drugs
Diseases
GWAS		Alzheimer's disease (APOE e4 interaction) ( 28183528) Automobile speeding propensity ( 30643258) HDL cholesterol ( 30275531) Heel bone mineral density ( 30598549) Height ( 28552196 20881960 25282103 31562340) Hip circumference ( 28552196) Hip circumference adjusted for BMI ( 28552196) Nevus count or cutaneous melanoma ( 30429480) Serum urate levels in chronic kidney disease ( 30181573) Weight ( 28552196)
Interacting Genes		25 interacting genes: CBLC CREBBP DACH1 EPHA2 ERGIC1 FBXO7 GLIS1 GLIS2 GLRX LATS2 LLPH MAP2K3 MAPK14 MYC NFIB NSD3 RELA RFX1 SOX3 TEAD2 TKTL2 TLX1 TPD52L3 ZCCHC14 ZKSCAN7	37 interacting genes: AKT1 ARNT AURKA BCL2L15 BECN1 CCND2 CDK4 CDK6 CDKN2A CDKN2B DACH1 EPHA2 FGFR4 FZR1 GLIS1 GLIS2 HGF HIF1A LATS2 MAP2K3 MAP2K5 MAP3K5 MYC NCOA1 NEDD4 NFIC NSD3 RAF1 RASSF1 SAA2 SOX3 STK11 TERT TP53 USF2 VGLL1 YAP1
Entrez ID		4782	8463
HPRD ID		09009	03432
Ensembl ID		ENSG00000141905	ENSG00000074219
Uniprot IDs		B7Z4T6 P08651	A0A024QZE2 Q15562
PDB IDs			3L15 5DQ8 5DQE 5EMV 5HGU 6E5G
Enriched GO Terms of Interacting Partners?
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