NFIC and GLRX

Number of citations of the paper that reports this interaction (PubMedID 9417094)
21

Data Source:
HPRD (in vitro, in vivo)

		NFIC	GLRX
Description		nuclear factor I C	glutaredoxin
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Fibrillar Center Nucleus Nucleoplasm	Cell Nucleus Cytosol Extracellular Exosome
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity	Electron Transfer Activity Glutathione Disulfide Oxidoreductase Activity Protein N-terminus Binding Glutathione Oxidoreductase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Replication Transcription By RNA Polymerase II Odontogenesis Of Dentin-containing Tooth Positive Regulation Of Transcription By RNA Polymerase II	Nucleobase-containing Small Molecule Interconversion Electron Transport Chain Cell Redox Homeostasis Positive Regulation Of Membrane Potential Protein Deglutathionylation Positive Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways		RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation	Interconversion of nucleotide di- and triphosphates
Drugs			Glutathione
Diseases
GWAS		Alzheimer's disease (APOE e4 interaction) ( 28183528) Automobile speeding propensity ( 30643258) HDL cholesterol ( 30275531) Heel bone mineral density ( 30598549) Height ( 28552196 20881960 25282103 31562340) Hip circumference ( 28552196) Hip circumference adjusted for BMI ( 28552196) Nevus count or cutaneous melanoma ( 30429480) Serum urate levels in chronic kidney disease ( 30181573) Weight ( 28552196)	High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Metabolite levels ( 23823483) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		25 interacting genes: CBLC CREBBP DACH1 EPHA2 ERGIC1 FBXO7 GLIS1 GLIS2 GLRX LATS2 LLPH MAP2K3 MAPK14 MYC NFIB NSD3 RELA RFX1 SOX3 TEAD2 TKTL2 TLX1 TPD52L3 ZCCHC14 ZKSCAN7	7 interacting genes: AQP5 CASP3 GOT2 MAP3K5 MMP23B NFIC PTPN1
Entrez ID		4782	2745
HPRD ID		09009	02707
Ensembl ID		ENSG00000141905	ENSG00000173221
Uniprot IDs		B7Z4T6 P08651	A0A024RAM2 P35754
PDB IDs			1B4Q 1JHB 4RQR
Enriched GO Terms of Interacting Partners?
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