NFE2 and MAFG

Number of citations of the paper that reports this interaction (PubMedID 9150357)
36

Data Source:
HPRD (in vivo, in vitro)

		NFE2	MAFG
Description		nuclear factor, erythroid 2	MAF bZIP transcription factor G
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm PML Body Protein-DNA Complex	Cell Nucleus Nucleoplasm
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Proximal Promoter Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Sequence-specific DNA Binding Protein N-terminus Binding WW Domain Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Protein Heterodimerization Activity
	Biological Process	Nucleosome Disassembly Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Blood Coagulation Hemostasis Blood Circulation Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription, DNA-templated	In Utero Embryonic Development Blood Coagulation Adult Behavior Regulation Of Cellular PH Regulation Of Cell Proliferation Regulation Of Epidermal Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production	Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Chronotype ( 30696823) Mean platelet volume ( 22139419 24026423) Platelet count ( 29403010 27863252) Plateletcrit ( 27863252) Red cell distribution width ( 28957414) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		22 interacting genes: ATF4 BTRC CREBBP ELF5 HMGN1 ITCH KAT2B MAFF MAFG MAFK MAPK8 NEDD4 NFE2L2 NFE2L3 PEX14 PHYHIP PRIM1 SCAND1 SSX5 TXN WWP1 YAP1	25 interacting genes: ATF3 BACH2 BATF3 CHD3 CREBBP CYP2E1 DDIT3 GTF2A1L HIF1A HOXD12 MAF MAFF MAPK3 MED31 NFE2 NFE2L1 NFE2L2 NFIL3 PAX6 PIDD1 PPP1CA PRRX1 RBM48 SNRPN VIM
Entrez ID		4778	4097
HPRD ID		09030	03605
Ensembl ID		ENSG00000123405	ENSG00000197063
Uniprot IDs		A8K3E0 Q16621	A0A024R8X1 O15525
PDB IDs		1LVX 2KZ5
Enriched GO Terms of Interacting Partners?
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