NEK3 and CDCA8

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		NEK3	CDCA8
Description		NIMA related kinase 3	cell division cycle associated 8
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Axon	Chromosome, Centromeric Region Cell Nucleoplasm Nucleolus Cytosol Chromocenter Midbody Chromosome Passenger Complex Protein-containing Complex Intercellular Bridge Spindle Midzone
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding	Protein Binding
	Biological Process	Mitotic Cell Cycle Protein Phosphorylation Establishment Of Cell Polarity Neuron Projection Morphogenesis Cell Division Regulation Of Tubulin Deacetylation	Mitotic Sister Chromatid Segregation Mitotic Metaphase Plate Congression Chromosome Organization Cell Division
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA replication proteins RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Axial length ( 24144296) Eyebrow thickness ( 26926045)
Interacting Genes		6 interacting genes: BPGM CDCA8 NMNAT1 PRLR VAV1 VAV2	14 interacting genes: AURKB BIRC5 H3C14 HLA-DRB3 INCENP MAPKAPK5 NEK3 PIAS2 RANBP2 SENP3 SGO1 SGO2 TTK UBE2I
Entrez ID		4752	55143
HPRD ID		04954	13017
Ensembl ID		ENSG00000136098	ENSG00000134690
Uniprot IDs		P51956 Q6ZN64	Q53HL2
PDB IDs			2KDD 2QFA 2RAW 2RAX
Enriched GO Terms of Interacting Partners?
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